Analysis of the Current Situation of Antibiotics Use in China: A Hospital-Based Perspective

Therapeutic Innovation & Regulatory Science
Jianhong TaoChuanbin Wu

Abstract

To investigate the present situation of antibiotics use in selected hospitals in China according to 2 indicators: hospital-based market sales and frequency of usage; based on this information, to assess the government's containment policies toward antibiotics overuse. Marketing and clinical usage data of antibiotics in 420 selected hospitals from 21 major cities and 1 district in China during 2008-2011 were collected and analyzed. Usage frequency was measured by the defined daily dose (DDD) analytic approaches recommended by World Health Organization (WHO), and the growth rate of DDDs per patient was compared for 3 categories of antibiotics: nonlimited (first line), limited (second line), and specially controlled (third line). During the period studied, an obvious slowdown was observed in both sales value and the growth of sales volume for the 3 categories. With respect to frequency, both limited-level and specially controlled level antibiotics with high cost and low safety and effectiveness showed an evident decline in the growth rate of DDDs per patient ( P < .05). However, no significant decline was found for nonlimited antibiotics ( P > .05). The Chinese government's containment policies toward antibiotics overuse are begin...Continue Reading

References

Jan 1, 2008·The Journal of Nutrition, Health & Aging·P K LamD Wingard
May 11, 2011·Bulletin of the World Health Organization·Emily LeungUNKNOWN World Health Organization World Health Day Antimicrobial Resistance Technical Working Group
Mar 23, 2012·Pharmacoepidemiology and Drug Safety·Lida TengKiichiro Tsutani
Jun 6, 2012·Expert Opinion on Drug Delivery·Lesheng TengRobert J Lee

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Citations

Dec 14, 2019·The Journal of Antimicrobial Chemotherapy·Jane Mingjie LimClarence C Tam
Jan 1, 2015·Therapeutic Innovation & Regulatory Science·Yun-Feng LaiYi-Tao Wang

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