Analysis of the efficacy of specific immunotherapy of allergic rhinitis after withdrawal of dust mites drops in about one year

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
T QiuY Xu

Abstract

Objective: To analyze the validity and related factors of sublingual immunotherapy of allergic rhinitis after withdrawal of dust mites drops in about one year. Method:In Renmin Hospital of Wuhan University 87 patients with allergic rhinitis whose allergen for dust mites from June 2007 to December 2011 were retrospectively analysed. The effect of sublingual immunotherapy and its related factors were evaluated by the symptoms and signs. The data was analysed by Logistic regression. Result: The response rate of samples is 54.0%. There are 36 patient having been treating over one year,the compliance rate is 41.4%. By using logistic regression results are as follows. The efficacy is related with treatment time(P <0.05),not are gender and age(P >0.05). When treatment time is less than 3 months,the validity is 41.9%. The validity of 3-12 months is 70.0%,The one of>12-18 months is 37.5%, The one of more than 18 months is 70.0%.Conclusion:The long-term efficacy of dust mites drops is positive correlation with time. But in 12-18 months condition can be waving. So clinician should supervise and urge patients and treat the adverse reactions properly, which can improve the effect of desensitization therapy and quality of life.

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