PMID: 8574053Jan 1, 1995

Analysis of the factors influencing the quality of life of patients with advanced or recurrent breast cancer

Surgery Today
K ShimozumaK Ichihara

Abstract

To investigate the factors influencing the quality of life (QOL) of Japanese patients with advanced or recurrent breast cancer, a newly developed QOL questionnaire, "The QOL Questionnaire for Cancer Patients Treated with Anticancer Drugs" (QOL-ACD), was answered by 23 patients, and a multiple regression analysis was performed. The demographic and medical factors relating to the overall QOL score and to the four categories of the QOL-ACD, namely (1) activity, (2) physical condition, (3) psychological condition, and (4) social relationships, were analyzed. The results indicated that skin metastasis, a heavier body weight, and bone metastasis had a strong negative influence on the overall QOL scroe, whereas endocrine therapy, the existence of a primary lesion, and more extensive first surgery had a strong positive influence on it. With regard to the analysis of the four categories, endocrine therapy was found to be positively related to all four categories. The multiple correlation coefficient (R) between the estimated overall QOL score and the observed overall QOL score was about 0.77. The results of this analysis showed that endocrine therapy can improve the QOL of patients with advanced or recurrent breast cancer, and that the ...Continue Reading

References

Jun 17, 1992·Journal of the National Cancer Institute·Y OheH Ohmatsu
Aug 11, 1992·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C PozoK C Clark
Jun 1, 1991·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G M KiebertC J van de Velde
Jan 1, 1990·Journal of Clinical Epidemiology·P A GanzH L Cheng
Jan 1, 1988·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·N K AaronsonS Ahmedzai
Dec 1, 1988·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M N LevineV H Bramwell
Jul 1, 1986·Arthritis and Rheumatism·C D Lorish, R Maisiak
Jun 1, 1985·Journal of the American Geriatrics Society·P A GanzR L Heinrich
Jun 1, 1983·Pharmacological Research Communications·G LelliF Pannuti
May 1, 1984·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H SchipperM Levitt
Jul 1, 1984·British Journal of Cancer·P J SelbyN F Boyd
Aug 23, 1984·The New England Journal of Medicine·B R CassilethA N Tenaglia
Jan 1, 1981·Journal of Chronic Diseases·W O SpitzerB R Catchlove
Dec 30, 1994·Breast Cancer : the Journal of the Japanese Breast Cancer Society·K ShimozumaK Ota
Apr 30, 1995·Breast Cancer : the Journal of the Japanese Breast Cancer Society·K ShimozumaT Kiyono

Citations

Oct 31, 1995·Breast Cancer : the Journal of the Japanese Breast Cancer Society·K ShimozumaK Ichihara
Aug 4, 2007·Breast Cancer Research and Treatment·Amy Trentham-DietzJohn M Hampton
Nov 10, 2000·International Journal of Radiation Oncology, Biology, Physics·W JanniT Genz
Aug 2, 2003·Breast Cancer Research and Treatment·Aminah JatoiRichard Pagano
Sep 5, 2003·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Takahiro OkamotoTask Force of the Japanese Breast Cancer Society for 'The Development of Guidelines for Quality of Life Assessment Studies o
Mar 31, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Alexander KreuterKerstin Lommel
Aug 27, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Daniel E SprattChristopher A Barker
Feb 28, 2018·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Andreas RothfussSven Clausen

Related Concepts

Self Care (Rehabilitation)
Mammary Neoplasms, Human
Gender Relations
Neoplasm Recurrence, Local
Quality of Life
Questionnaire Design
Regression Analysis

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.