Analysis of the genomic response of a wine yeast to rehydration and inoculation

Applied Microbiology and Biotechnology
T RossignolBruno Blondin


We used DNA microarrays to study the transcriptome of a wine yeast before and after rehydration and during the first hours following inoculation of a synthetic must. There was a substantial transcriptional remodeling during this period, including 1,874 genes regulated more than threefold. Dried yeasts displayed an expression profile typical of respiratory-grown cells starved for nitrogen and carbon and which had been highly stressed. During rehydration, many genes involved in biosynthetic pathways, in transcription or in protein synthesis were coordinately induced while genes subject to glucose repression were down-regulated. The transcriptional response was very rapid indicating that yeast quickly recovered the capacity to sense environmental signals and to respond appropriately. Our data show that genes involved in the general stress response were repressed during rehydration while acid stress specific genes were induced probably in response to organic acid accumulation. The glycolytic genes and acid stress-responsive genes were simultaneously and transiently repressed after inoculation into the fermentation medium suggesting that regulation of glycolytic genes may correspond to an adjustment to the energetic needs of the cel...Continue Reading


Oct 1, 1991·Molecular and Cellular Biology·P A MooreA J Brown
Mar 21, 1993·Biochimica Et Biophysica Acta·E C EleutherioA D Panek
Jun 11, 1996·Proceedings of the National Academy of Sciences of the United States of America·A P Schmitt, K McEntee
Apr 17, 1999·Molecular and Cellular Biology·Ismaïl IraquiAntonio Urrestarazu
Jan 5, 2000·Genes & Development·M E CardenasJ Heitman
Sep 6, 2000·Journal of Applied Microbiology·P V AttfieldP J Bell
Dec 5, 2000·Molecular Biology of the Cell·A P GaschP O Brown
Jan 12, 2001·FEMS Microbiology Reviews·Jean François, J L Parrou
Feb 17, 2001·Molecular Biology of the Cell·H C CaustonR A Young
Apr 6, 2002·Bioinformatics·G DidierA Hénaut
May 10, 2002·International Journal of Food Microbiology·Jeanette Brejning, Lene Jespersen
Jun 28, 2002·Systematic and Applied Microbiology·Roberto Pérez-TorradoMarcel Lí del Olmo
Nov 15, 2002·BMC Bioinformatics·Mark D RobinsonTimothy R Hughes
Feb 18, 2003·Molecular and Cellular Biology·Angelika KrenKarl Kuchler
Mar 13, 2003·Archives of Microbiology·Jeanette BrejningNils Arneborg
Aug 2, 2003·International Journal of Food Microbiology·Maria Teresa NovoAlberto Mas
Mar 26, 2004·FEMS Yeast Research·Gemma BeltranJosé Manuel Guillamón
Jul 17, 2008·Comparative and Functional Genomics·N C HauserJ E Pérez-Ortín


Oct 17, 2008·Applied Microbiology and Biotechnology·Jing-Sheng ChengYing-Jin Yuan
Aug 5, 2011·Applied Microbiology and Biotechnology·Antonella CostantiniEmilia Garcia-Moruno
Jun 28, 2007·Current Genetics·Virginie GaleoteBruno Blondin
Oct 14, 2010·Applied Microbiology and Biotechnology·Elena Jiménez-MartíMarcel-li del Olmo
Dec 12, 2012·Trends in Genetics : TIG·Anthony R BornemanIsak S Pretorius
Dec 3, 2011·International Journal of Food Microbiology·Vanessa PenachoRamon Gonzalez
Nov 13, 2008·Journal of Bioscience and Bioengineering·Toshihide NakamuraJun Shima
Jun 26, 2007·Trends in Biotechnology·Anthony R BornemanIsak S Pretorius
Feb 28, 2009·Journal of Applied Microbiology·T RossignolBruno Blondin
Apr 18, 2012·Journal of Applied Microbiology·Z SalvadóJosé Manuel Guillamón
Mar 20, 2014·Biotechnology Journal·Esther Gamero-SandemetrioE Matallana
Jul 25, 2007·FEMS Microbiology Reviews·Brian R GibsonKatherine A Smart
May 22, 2010·FEMS Microbiology Letters·Yuliya TrofimovaAlexander Rapoport
May 28, 2008·FEMS Yeast Research·Zoel SalvadóJosé Manuel Guillamón
Mar 25, 2015·PloS One·Gema López-MartínezRicardo Cordero-Otero
Sep 29, 2007·Advances in Food and Nutrition Research·Linda F BissonLucy Joseph
Oct 8, 2016·Letters in Applied Microbiology·E Matallana, A Aranda
Sep 28, 2007·Yeast·Francisco PizarroEduardo Agosin
Aug 19, 2017·FEMS Yeast Research·David FerreiraSylvie Dequin
Dec 29, 2017·Molecular Biology of the Cell·Catherine TesnièreFrédéric Bigey

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