Analysis of the performance of 100% rapid review using an average time of 1 and 2 minutes according to the quality of cervical cytology specimens

Cytopathology : Official Journal of the British Society for Clinical Cytology
Edna J C ManriqueRita G Amaral

Abstract

To compare the performance of the 100% rapid review method carried out in a mean time of either 1 or 2 minutes according to cytological final result, and to assess whether the presence of obscuring factors in cervical smear samples affects the frequency of false-negative results. A total of 5,235 smears classified as negative (93.0%) or unsatisfactory (2.1%) at routine screening were submitted to 100% rapid review using mean times of 1 and 2 minutes. Of the 5,235 smears submitted to 1-minute rapid review, 88 were considered suspect and of these, 45 were confirmed as abnormal in the cytological final result. When the time used was 2 minutes, 67 smears were considered suspect, 44 of which were confirmed as abnormal. Sensitivity and specificity were similar in the 1- and 2-minute reviews. In smears in which samples were satisfactory and had no obscuring factors, sensitivity and specificity were 64.2% and 98.9% and 61.5% and 99.5% for the 1- and 2-minute reviews, respectively. In comparison, in smears in which the sample was satisfactory for analysis but partially obscured (50-75%), sensitivity and specificity were 64.7% and 99.9% and 70.6% and 99.8% for the 1- and 2-minute reviews, respectively. The method of rapid review of 100% ...Continue Reading

References

Aug 8, 2001·Cytopathology : Official Journal of the British Society for Clinical Cytology·N DuddingS Rice
Sep 25, 2002·Cytopathology : Official Journal of the British Society for Clinical Cytology·D BrookeJ Sutton
Oct 3, 2002·Journal of the National Cancer Institute·Jeanne S MandelblattPaul D Blumenthal
Sep 27, 2003·Cytopathology : Official Journal of the British Society for Clinical Cytology·J SmithR Deacon-Smith
Sep 7, 2004·Diagnostic Cytopathology·Ana P Martins SebastiãoLuiz F Bleggi-Torres
Jan 22, 2005·Cancer·Gary W Gill
Jun 22, 2005·Acta Cytologica·Rita Goreti AmaralEliana Borin Montemor
May 25, 2006·Cytopathology : Official Journal of the British Society for Clinical Cytology·E J C ManriqueL C Zeferino
May 25, 2006·Cytopathology : Official Journal of the British Society for Clinical Cytology·M PajtlerV Milicić-Juhas
Dec 19, 2006·Diagnostic Cytopathology·Eliana Borin Lopes MontemorKari J Syrjanen
Mar 14, 2007·Diagnostic Cytopathology·Andrea Alves RibeiroSilvia Helena Rabelo-Santos
Apr 3, 2007·Cytopathology : Official Journal of the British Society for Clinical Cytology·H G WienerA Herbert
Apr 30, 2008·Cancer·Andrew A Renshaw
Aug 21, 2008·Cytopathology : Official Journal of the British Society for Clinical Cytology·D MooreT Walker
Jul 21, 2009·Cancer·Andrew A Renshaw
Oct 7, 2009·Indian Journal of Pathology & Microbiology·Neelam Sood, Vikas Singh

❮ Previous
Next ❯

Citations

Dec 20, 2011·American Journal of Clinical Pathology·Heather S CurrensStephen S Raab
May 23, 2018·Acta Cytologica·José Queiroz FilhoAna Katherine Gonçalves
Jun 16, 2018·Cytopathology : Official Journal of the British Society for Clinical Cytology·A H G TobiasC M Carneiro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.