PMID: 9434303Jan 22, 1998Paper

Analysis of the reconstructibility and noise properties of scattered photons in 99mTc SPECT

Physics in Medicine and Biology
D J KadrmasB M Tsui

Abstract

Since scattered photons carry degraded spatial information, scatter is typically considered a source of contamination in SPECT. However, with the advent of scatter modelling methods and reconstruction-based scatter compensation (RBSC), it may be possible to utilize scattered data in a productive manner. In this work we analyse the reconstructibility of scattered photon projection data and investigate the potential for using scattered photons to reduce the noise levels of SPECT images. We have simulated projection data for an elliptical phantom containing three cold rods in a uniform background of 99mTc activity. A variety of photopeak and scatter energy windows were formed, as well as corresponding RBSC transfer matrices. Each statistically weighted matrix was decomposed using SVD and analysed in terms of reconstructibility and noise properties. Results indicate that scattered photons contain sufficient information to reconstruct the source activity, but the scatter-only matrices are very poorly conditioned. We have also evaluated several methods of utilizing scattered events via RBSC, and compared them with other, idealized methods of handling scatter. It was found that scattered photons can be used productively when photopeak...Continue Reading

References

Aug 1, 1989·Computer Methods and Programs in Biomedicine·M Ljungberg, S E Strand
Jan 1, 1992·IEEE Transactions on Medical Imaging·M F SmithR E Coleman
Jan 1, 1991·IEEE Transactions on Medical Imaging·K OgawaS Hashimoto
Jan 1, 1988·IEEE Transactions on Medical Imaging·J C YanchS Webb
Jan 1, 1989·IEEE Transactions on Medical Imaging·D GagnonG Dupras
Aug 1, 1996·IEEE Transactions on Nuclear Science·Dan J KadrmasBenjamin M W Tsui

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Citations

Jan 4, 2001·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·F J BeekmanM A Viergever
Sep 3, 1999·Physics in Medicine and Biology·D J KadrmasG T Gullberg
Feb 15, 2011·Physics in Medicine and Biology·Krzysztof KacperskiBrian F Hutton
Jul 13, 2011·International Journal of Biomedical Imaging·M K NguyenH Zaidi

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