Analysis of three-chamber view conventional and tagged cine MRI in patients with suspected hypertrophic cardiomyopathy.

Magma
Teodora ChitiboiLeon Axel

Abstract

To investigate the potential value of adding a tagged three-chamber (3Ch) cine to clinical hypertrophic cardiomyopathy (HCM) magnetic resonance imaging (MRI) protocols, including to help distinguish HCM patients with regionally impaired cardiac function. Forty-eight HCM patients, five patients with "septal knuckle" (SK), and 20 healthy volunteers underwent MRI at 1.5T; a tagged 3Ch cine was added to the protocol. Regional strain, myocardial wall thickness, and mitral valve leaflet lengths were measured in the 3Ch view. In HCM, we found a reduced tangential strain with decreased diastolic relaxation in both hypertrophied (p = 0.003) and remote segments (p = 0.035). Strain in the basal septum correlated with the length of the coaptation zone + residual leaflet (r = 0.48, p < 0.001). In the basal free wall, patients with SK had faster relaxation compared to HCM patients with septal hypertrophy. The 3Ch tagged MRI sequence provides useful information for the examination of suspected HCM patients, with minimal additional time cost. Local wall function is closely associated with morphological changes of the mitral apparatus measured in the same plane and may provide insights into mechanisms of obstruction. The additional strain infor...Continue Reading

References

Mar 11, 1991·The Journal of Clinical Investigation·J K GwathmeyJ P Morgan
May 1, 1989·Journal of the American College of Cardiology·E G CapeR A Levine
Jun 1, 1989·Radiology·L Axel, L Dougherty
Jun 1, 1995·Histopathology·M J Davies, W J McKenna
Sep 1, 1993·Journal of the American College of Cardiology·M V SherridE M Dwyer
Mar 4, 1999·Journal of Magnetic Resonance·A H AletrasH Wen
Mar 12, 2002·JAMA : the Journal of the American Medical Association·Barry J Maron
Jan 24, 2003·The New England Journal of Medicine·Martin S MaronBarry J Maron
May 11, 2005·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Caroline PetitjeanPhilippe Cluzel
Aug 7, 2010·Journal of the American College of Cardiology·Rory O'HanlonSanjay K Prasad
Feb 22, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Radwa A NoureldinDavid A Bluemke
Aug 4, 2012·The Annals of Thoracic Surgery·Sandhya K BalaramDaniel G Swistel
Dec 10, 2013·Current Cardiology Reviews·Mihir A KelshikerDarlington O Okonko
Aug 15, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Dan G HalpernMark V Sherrid
Oct 29, 2015·European Heart Journal·Otto A SmisethStig Urheim
Apr 16, 2016·Journal of the American College of Cardiology·Mark V SherridDaniel G Swistel
May 5, 2017·Journal of Magnetic Resonance Imaging : JMRI·Teodora Chitiboi, Leon Axel
Mar 6, 2018·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Robert G NampiaparampilMark V Sherrid

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