Analysis of three ultrasound elastography techniques for grading liver fibrosis in patients with chronic hepatitis B

La Radiologia medica
Xinping RenJianqiao Zhou

Abstract

Evaluation of liver fibrosis is important to assess prognosis and guide the treatment for chronic hepatitis B. To analyze and compare transient, point, and two-dimensional (2D) shear wave elastography techniques in grading the liver fibrosis. Based on the severity of liver inflammation and fibrosis (Scheuer criteria), 158 patients with chronic hepatitis B were assigned into group 1 (either G or S classification < 2) or group 2 (either G or S classification ≥ 2). Group 2 patients commonly require anti-viral treatment. All patients received transient (FibroScan), point (STQ), and 2D (STE) elastography examinations. Receiver operating characteristic curves were calculated from three elastography techniques in individual or in combination. A total of 158 patients were enrolled into the study, with 39.2% (62) female and mean age of 42.8 (standard deviation 19.1) years old. Transient elastography could not differentiate between group 1 and group 2 patients (P = 0.12), whereas point and 2D elastography examinations could distinguish patients in group 1 from group 2 (P < 0.01 for both STQ and STE). Administration of combined three elastography techniques showed the best diagnostic accuracy (90.1%) for liver fibrosis, which was confirme...Continue Reading

References

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Apr 25, 2017·Theranostics·Rosa M S SigristJuergen K Willmann
Jun 7, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Guangqin XiaoGang Wu

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Citations

Sep 11, 2019·Liver International : Official Journal of the International Association for the Study of the Liver·Malika KhodjaevaErkin Musabaev
May 16, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Lei HuWen Zhong
Jan 26, 2021·La Radiologia medica·Giulio ArgaliaAndrea Giovagnoni

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