Abstract
Antimicrobial resistance, including plasmid-mediated resistance, among Bacteroides fragilis group species is well documented. A 5-year (1990-1994) prospective, eight-center survey of 3,177 clinical isolates of Bacteroides species was undertaken to review trends in resistance, using the breakpoints for full and intermediate susceptibility established by the National Committee for Clinical Laboratory Standards. No documented resistance to either metronidazole or chloramphenicol was found in this survey. Among B. fragilis isolates virtually no resistance was seen to imipenem, meropenem, ampicillin/sulbactam, piperacillin/tazobactam, or ticarcillin/clavulanate. Significant increases in resistance among B. fragilis isolates to cefotetan, ceftizoxime, and clindamycin (p < .01) were noted. Resistance to cefoxitin remained unchanged. Among the non-fragilis species of the B. fragilis group, there was virtually no resistance to imipenem, meropenem, chloramphenicol, or metronidazole. The three beta-lactamase inhibitors had increasing levels of resistance, although 95%-98% of strains were susceptible (p < .05). There was a significant decline in cefoxitin, cefmetazole, and clindamycin activity over time against these strains (p <.01). Ther...Continue Reading
Citations
Oct 15, 2009·Folia Microbiologica·D Chmelar
Jun 5, 2003·Journal of Microbiological Methods·Curtis J DonskeyLouis B Rice
Jan 10, 2002·Infectious Disease Clinics of North America·T F Smith
Jun 17, 2000·International Journal of Antimicrobial Agents·M E Falagas, E Siakavellas
May 18, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H Jorgensen, M J Ferraro
Jun 14, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M H NguyenD R Snydman
Dec 29, 2011·Antimicrobial Agents and Chemotherapy·James A KarlowskyGeorge G Zhanel
Sep 18, 2002·Antimicrobial Agents and Chemotherapy·D R SnydmanS L Gorbach
Aug 17, 2002·Antimicrobial Agents and Chemotherapy·Lee-Jene TengKwen-Tay Luh
Feb 26, 2004·Antimicrobial Agents and Chemotherapy·N V JacobusD R Snydman
Apr 9, 2004·Journal of Clinical Microbiology·Lee-Jene TengJui-Chang Tsai
Sep 15, 2004·Journal of Clinical Microbiology·Jeffrey M SchapiroAjit P Limaye
Aug 12, 2009·Infectious Disease Clinics of North America·Joseph S Solomkin, John Mazuski
Apr 30, 1999·Mayo Clinic Proceedings·W C Hellinger, N S Brewer
Aug 5, 2006·Anaerobe·H FangC E Nord
May 10, 2007·FEMS Microbiology Letters·Fernanda S AlmeidaMario J Avila-Campos
Oct 3, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph S SolomkinUNKNOWN Infectious Diseases Society of America
Jul 27, 2004·Memórias do Instituto Oswaldo Cruz·Viviane Nakano, Mario J Avila-Campos
Sep 3, 1999·Mayo Clinic Proceedings·M J Kasten
Nov 8, 2017·Antibiotics·Márió GajdácsEdit Urbán
Feb 19, 2010·Surgical Infections·Joseph S SolomkinJohn G Bartlett
Jun 3, 2015·Antimicrobial Agents and Chemotherapy·Janessa M SmithSara E Cosgrove
Mar 8, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David W Hecht
Apr 21, 1999·The Journal of Laryngology and Otology·J M KlossekP Beutter
Aug 13, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D R SnydmanS L Gorbach
Oct 3, 1999·Antimicrobial Agents and Chemotherapy·D R SnydmanS L Gorbach
Sep 3, 1999·Antimicrobial Agents and Chemotherapy·C BetriuJ J Picazo
Aug 13, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D E RoeD W Hecht
Aug 13, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ellie J C Goldstein
Dec 26, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph S SolomkinJohn G Bartlett
Oct 3, 1999·Antimicrobial Agents and Chemotherapy·A C LabbéF Lamothe
Sep 26, 1997·Antimicrobial Agents and Chemotherapy·M E FalagasD R Snydman
Apr 4, 2000·Journal of Clinical Microbiology·L J TengK T Luh