Analysis of word number and content in discourse of patients with mild to moderate Alzheimer's disease

Dementia & Neuropsychologia
Juliana Onofre de LiraKarin Zazo Ortiz

Abstract

Alzheimer's disease (AD) is characterized by impairments in memory and other cognitive functions such as language, which can be affected in all aspects including discourse. A picture description task is considered an effective way of obtaining a discourse sample whose key feature is the ability to retrieve appropriate lexical items. There is no consensus on findings showing that performance in content processing of spoken discourse deteriorates from the mildest phase of AD. To compare the quantity and quality of discourse among patients with mild to moderate AD and controls. A cross-sectional study was designed. Subjects aged 50 years and older of both sexes, with one year or more of education, were divided into three groups: control (CG), mild AD (ADG1) and moderate AD (ADG2). Participants were asked to describe the "cookie theft" picture. The total number of complete words spoken and information units (IU) were included in the analysis. There was no significant difference among groups in terms of age, schooling and sex. For number of words spoken, the CG performed significantly better than both the ADG 1 and ADG2, but no difference between the two latter groups was found. CG produced almost twice as many information units as ...Continue Reading

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Citations

Aug 15, 2018·Journal of Alzheimer's Disease : JAD·Antoine SlegersSimona Maria Brambati
Sep 16, 2020·Journal of the American Medical Informatics Association : JAMIA·Ulla PettiAnna Korhonen
May 14, 2016·Journal of Clinical and Experimental Neuropsychology·Gitit Kavé, Mira Goral
Apr 20, 2018·Journal of Clinical and Experimental Neuropsychology·Kimberly D MuellerLyn S Turkstra
Jan 1, 2020·Exploration of Medicine·Honghuang LinRhoda Au
Apr 13, 2021·Journal of Speech, Language, and Hearing Research : JSLHR·Fernanda SchneiderLilian Cristine Hübner

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