PMID: 29071909Jun 25, 2016Paper

Analysis on Influencing Factors of Acupoint Injection of Drugs for Improving Allergic Rhinitis in Rats

Zhen ci yan jiu = Acupuncture research
Meng YangYuan Zhang

Abstract

To observe the therapeutic effect of acupoint injection of mixture solution of lidocaine, dexa-methasone (DX) and transfer factor on symptoms and serum histamine contents in allergic rhinitis (AR) rats, so as to differentiate the role of acupoint stimulation or drug factor influencing the therapeutic effect. SD rats were randomized into normal (n=8), model, non-acupoint-drug injection, acupoint-drug injection and acupoint-saline injection groups (n=11 in each group). The AR model was established by intraperitoneal injection of suspension of ovalbumin (0.3 mg) and aluminum hydroxide (30 mg), 1 mL, once every other day for 7 days, followed by nose-dripping of 5% ovalbumin (50 μL) for other 7 days. The AR scores for rhinocnesmus severity (1-2 points), sneezing times (1-3 points) and nasal discharge quantity (1-3 points) were assessed by cumulative quantification scoring method. "Yintang" (EX-HN 3) and bilateral "Yingxiang" (LI 20) were used for acupoint injection of mixture solution of 1% Lidocaine, DX and transfer factor (1:1:1, 0.1 mL/acupoint), once every other day for 7 days. The non-acupoints were located at the bilateral sub-costal regions and the mid-point between the left "Houhai" (GV 1) and "Huantiao" (GB 30).The same dos...Continue Reading

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