PMID: 2102260Jan 1, 1990Paper

Analytical methodologies for the quantitation of platinum anti-cancer drugs and related compounds in biological media

Journal of Pharmaceutical and Biomedical Analysis
W A de WaalJ C Kraak

Abstract

The methods for analysis of platinum-based anti-cancer drugs in biological media are reviewed in this paper. Although emphasis is placed on cisplatin, attention is also given to several of its analogues (carboplatin, iproplatin) and their degradation and biotransformation products. In an introductory section a short description is given of the historical background and the clinical applications of cisplatin. Reactions occurring in the body and in aqueous solutions are discussed because of their implications for the design of analytical procedures. After a detailed description of sample preparation and storage, attention is focussed on the analytical techniques used for the determination of either total platinum levels or individual platinum-containing compounds. The techniques discussed include atomic absorption and emission spectrometry, derivatization reactions and several chromatographic techniques with different detection methods. The specific advantages and disadvantages of these techniques are discussed.

References

Sep 1, 1978·Chemico-biological Interactions·R C Manaka, W Wolf
Mar 1, 1979·Clinical Pharmacology and Therapeutics·P E GormleyR Cysyk
Jan 1, 1987·Cancer Chemotherapy and Pharmacology·L HegedüsH M Pinedo
Dec 1, 1987·Journal of Clinical Pharmacy and Therapeutics·G J SewellC G Rowland
Nov 1, 1987·Journal of Analytical Toxicology·F B LoM A Nazar
Aug 1, 1986·Analytical Chemistry·G M Schmid, D R Atherton
Aug 15, 1986·Clinica Chimica Acta; International Journal of Clinical Chemistry·C DominiciM A Castello
Jan 1, 1986·Cancer Chemotherapy and Pharmacology·W J van der Vijgh, I Klein
Oct 25, 1985·Pharmaceutisch Weekblad. Scientific Edition·J Reedijk, P H Lohman
May 1, 1985·Biochemical Pharmacology·P T Daley-Yates, D C McBrien
Feb 1, 1985·Journal of Pharmacokinetics and Biopharmaceutics·F F FarrisC L Litterst
Aug 1, 1985·Chemical & Pharmaceutical Bulletin·K InagakiY Kidani
Jul 1, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·J Smeyers-VerbekeD L Massart
May 1, 1984·Annals of Internal Medicine·P J Loehrer, L H Einhorn
Mar 1, 1984·Analytical Chemistry·K C MarshA J Repta
Mar 9, 1984·Journal of Chromatography·P A ReeceR L Richardson
Dec 19, 1984·Journal of Chromatography·B De SpiegeleerP De Moerloose
Jan 1, 1983·Therapeutic Drug Monitoring·R P Sharma, I R Edwards
Apr 1, 1983·Journal of Chromatographic Science·I S KrullL A Sternson
Apr 1, 1983·Journal of Pharmaceutical Sciences·C M RileyA J Repta

❮ Previous
Next ❯

Citations

Jan 1, 1994·Cancer Chemotherapy and Pharmacology·W P PetrosD L Trump
Jan 1, 1995·Cancer Chemotherapy and Pharmacology·D C ThompsonS G Chaney
Sep 18, 2012·European Journal of Clinical Pharmacology·P H CashinH Mahteme
Apr 2, 2010·Physical Chemistry Chemical Physics : PCCP·Seiji TakahashiToshihiro Fujii
Feb 1, 1997·Pharmaceutical Development and Technology·L García-ContrerasD R Lu
May 16, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Deanna N BellMark J McKeage
Jun 15, 2005·Rapid Communications in Mass Spectrometry : RCM·Yuan-Yuan ZhaoXing-Fang Li
Mar 29, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Allal Barroug, Melvin J Glimcher
Feb 23, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Frank van HarenMonique Steegers
Sep 28, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Miguel A Villalona-CaleroJon Holmlund
Nov 1, 1995·Journal of Pharmaceutical and Biomedical Analysis·G K PoonC F Barnard
Aug 1, 1996·Journal of Pharmaceutical Sciences·A AnderssonH Ehrsson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.