Analytical methods for the study of bioactive compounds from medicinally used Echinacea species

Journal of Pharmaceutical and Biomedical Analysis
Renato BruniFederica Pellati

Abstract

Echinacea purpurea (L.) Moench, Echinacea angustifolia DC. var. angustifolia and Echinacea pallida (Nutt.) Nutt. are frequently used as medicinal plants and their preparations are among the most widely used herbal medicines. The extracts from these species have shown a highly complex chemical composition, including polar compounds (caffeic acid derivatives, CADs), non-polar compounds (alkylamides and acetylenic secondary metabolites; essential oil) and high molecular weight constituents (polysaccharides and glycoproteins). All these chemical classes of compounds have demonstrated to possess interesting biological activities. In the light of all the above, this paper is focused on the analytical techniques, including sample preparation tools and chromatographic procedures, for the chemical analysis of bioactive compounds in medicinally used Echinacea species. Since sample preparation is considered to be a crucial step in the development of analytical methods for the determination of constituents present in herbal preparations, the strength and weakness of different extraction techniques are discussed. As regards the analysis of compounds present in Echinacea plant material and derivatives, the application of different techniques...Continue Reading

Citations

Oct 19, 2019·Biomolecules·Erin DobrangeWim Van den Ende
Nov 30, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chiara CavaliereAldo Laganà
Oct 20, 2020·Revista Brasileira De Farmacognosia : Orgão Oficial Da Sociedade Brasileira De Farmacognosia·Taiwo O ElufioyeAdeboye Adejare
May 25, 2021·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Wenqian XuHe Qian
Jul 16, 2021·Frontiers in Immunology·Giuseppe DerosaFrancesco Di Pierro

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