Analytical Sigma metrics: A review of Six Sigma implementation tools for medical laboratories

Biochemia Medica
Sten WestgardJames O Westgard

Abstract

Sigma metrics have become a useful tool for all parts of the quality control (QC) design process. Through the allowable total error model of laboratory testing, analytical assay performance can be judged on the Six Sigma scale. This not only allows benchmarking the performance of methods and instruments on a universal scale, it allows laboratories to easily visualize performance, optimize the QC rules and numbers of control measurements they implement, and now even schedule the frequency of running those controls.

References

Feb 10, 2000·Scandinavian Journal of Clinical and Laboratory Investigation·C RicósM Simón
Nov 19, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·James O Westgard
Jan 18, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Bedrich FriedeckyMarek Budina
Aug 2, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Christian H H SchoenmakersGerard Steen
Mar 13, 2014·Clinical Chemistry and Laboratory Medicine : CCLM·Koen HensSten Westgard
Nov 22, 2014·Clinical Chemistry and Laboratory Medicine : CCLM·Carmen PerichCallum G Fraser
Mar 5, 2015·Clinical Chemistry·Cas WeykampUNKNOWN IFCC Task Force on Implementation of HbA1c Standardization
Apr 18, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Anna Carobene
May 1, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Carmen RicósElisabet González-Lao
Jul 8, 2015·Annals of Clinical Biochemistry·James O Westgard, Sten A Westgard
Aug 25, 2015·Revista de calidad asistencial : organo de la Sociedad Española de Calidad Asistencial·R BlázquezF Ramón
Oct 2, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·James O Westgard
Nov 6, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Wytze P Oosterhuis, Elvar Theodorsson
Nov 19, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Mauro Panteghini, Sverre Sandberg
May 21, 2016·Clinical Chemistry·Martín Yago, Silvia Alcover
Aug 11, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Ferruccio CeriottiMauro Panteghini
Feb 6, 2017·Clinics in Laboratory Medicine·James O Westgard, Sten A Westgard
Feb 6, 2017·Clinics in Laboratory Medicine·Elvar Theodorsson
Feb 6, 2017·Clinics in Laboratory Medicine·Jamuna JairamanLee Suan Li
Feb 6, 2017·Clinics in Laboratory Medicine·Joseph Litten
Feb 6, 2017·Clinics in Laboratory Medicine·James O Westgard, Sten A Westgard
Feb 6, 2017·Clinics in Laboratory Medicine·Navapun Charuruks
Feb 27, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Hassan Bayat
Apr 22, 2017·Clinical Chemistry·Anna CarobeneUNKNOWN European Biological Variation Study of the EFLM Working Group on Biological Variation
Jun 9, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Graham R D JonesUNKNOWN EFLM Task Finish Group – Analytical Performance Specifications for EQAS (TFG-APSEQA)
Jul 20, 2017·Clinical Chemistry·Anna CarobeneUNKNOWN European Biological Variation Study of the EFLM Working Group on Biological Variation
Aug 11, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Wytze P OosterhuisElvar Theodorsson
Oct 17, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Mauro PanteghiniUNKNOWN Task Force on Performance Specifications in Laboratory Medicine of the European Federation of Clinical Chemistry and Laborat
Nov 4, 2017·Clinical Chemistry·James O WestgardSten A Westgard
Dec 10, 2017·Clinical Chemistry·Aasne K AarsandUNKNOWN European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation and Task and Finish

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Citations

Mar 7, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Martine J HollestelleMoniek P M de Maat
Oct 23, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Tommaso FasanoKatell Peoc'h
Nov 28, 2019·Journal of Clinical Laboratory Analysis·Bingfei ZhouYoude Cao
Sep 21, 2020·Journal of Clinical Laboratory Analysis·Yanming LiuWencan Cai
Sep 5, 2020·Journal of Analytical Toxicology·Christian TagwerkerDavid J Smith
Mar 25, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Huub H van Rossum, Daan van den Broek
Dec 15, 2020·Journal of Clinical Laboratory Analysis·Yong XiaLing Ji
Jun 2, 2021·The Journal of Applied Laboratory Medicine·Matthew FeldhammerJames H Nichols
Jul 19, 2021·International Journal of Laboratory Hematology·Wafaa Ahmed El-NeanaeyReham Abdel Haleem Abo Elwafa
Oct 5, 2021·Journal of Clinical Laboratory Analysis·Yanfen LuoSongbang Ou

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Software Mentioned

Six
OPSpecs
Sigma
EQA

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