PMID: 7007996Dec 1, 1980Paper

Anaphylactic shock in brown Norway rats with reagins and no precipitins in the blood (author's transl)

Pathologie-biologie
J DamasJ Lecomte

Abstract

Brown Norway rats have been actively sensitized against hen ovalbumine mixed with anti Bordella pertussis vaccine. After ten to twelve days, IgE are detected in the blood, but no precipitins. Anaphylactic shock induced by i.v. injection of 1 mg.100 g-1 body weight of ovalbumine is caracterized by a vascular collapse, the animal dying in about 15 minutes. This collapse is identical with the same general anaphylactic reaction as observed in the Wistar rats, which have large amounts of precipitins in the blood.

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.