PMID: 3754095Feb 1, 1986Paper

Anaphylactoid reaction complicating neonatal anaesthesia

Anaesthesia
E M PollockL R McNicol

Abstract

A three-week-old girl presented for surgery for congenital pyloric stenosis. The anaesthetic technique included intravenous induction with thiopentone and neuromuscular blockade with atracurium. The administration of these drugs was followed within 2-3 minutes by oedema of the eyelids and epiglottis, reduced peripheral circulation and central cyanosis. There was no previous exposure to either drug and no definite family history of allergy. Analysis of subsequent sequential blood samples indicated that the reaction mechanism was non-immune and was presumed to be due to pharmacological release of histamine.

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Citations

Feb 16, 2010·Annales Françaises D'anesthèsie Et De Rèanimation·P Dewachter, C Mouton-Faivre
Nov 23, 2013·Pediatric Neurology·Esad KokluSelmin Koklu
Sep 26, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Esad KokluErdal Avni Ariguloglu
Mar 5, 2014·Neonatal Network : NN·Esad KokluErdal Arvi Ariguloglu
Feb 1, 1988·Anaesthesia·A C FentonJ G Wandless
Mar 10, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ali BulbulSerdar Umit Sarici

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