PMID: 3768768Sep 1, 1986Paper

Anaphylactoid reaction to atracurium

Canadian Anaesthetists' Society Journal
J E Tetzlaff, M D Gellman

Abstract

Atracurium is a new intermediate-acting muscle relaxant, relatively devoid of cardiovascular effect in the clinical dose range. Histamine release is reported in a dose-dependent fashion, but below the threshold for haemodynamic effect within the recommended dose limits. We report a case of an anaphylactoid reaction to a low dose (0.2 mg X kg-1) of atracurium, and discuss the peculiar aspects of this case that predisposed the patient to this event.

References

Dec 1, 1978·Anesthesiology·F S Brauer, C R Ananthanarayan
Aug 1, 1985·British Journal of Anaesthesia·G G LaveryR K Mirakhur
May 1, 1973·British Journal of Anaesthesia·R W Buckland, A F Avery
Sep 26, 1974·The New England Journal of Medicine·K F Austen
Apr 1, 1971·British Journal of Anaesthesia·G R Kelman, B R Kennedy
Sep 1, 1973·British Journal of Anaesthesia·R M Clark
Mar 1, 1974·British Journal of Anaesthesia·D G Tweedie, P M Ordish
Jul 1, 1970·British Journal of Anaesthesia·B R Kennedy, G R Kelman
Jun 1, 1983·Anesthesia and Analgesia·M M Fisher, I Munro
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Sep 1, 1984·Anesthesia and Analgesia·S Mishima, T Yamamura

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.