PMID: 6814670Dec 4, 1982

Anaphylactoid reactions due to haemodialysis, haemofiltration, or membrane plasma separation

British Medical Journal
A J Nicholls, M M Platts

Abstract

A previously undescribed anaphylactoid reaction to haemodialysis, haemofiltration, or membrane plasma separation occurred in 15 patients receiving regular dialysis. The illness varied in severity from urticaria, sneezing, and watering of the eyes to severe bronchospasm and cardiovascular collapse, and began within a minute of blood being returned from the dialyser or filtration device to the patient. Reactions developed only when a dialyser sterilised with ethylene oxide was used for the first time and never after sterilisation with formalin. Several patients had more than one reaction while three had a reaction each time a new dialyser was used. Incorrect priming of the dialysers may be a partial explanation of these attacks, but the exact reason for their occurrence is unknown. This is a dramatic and potentially life-threatening syndrome that may not previously have been recognised as a reaction to dialysis.

References

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Citations

Oct 4, 1984·The New England Journal of Medicine·R M HakimF K Port
Feb 11, 2012·Seminars in Dialysis·Andre Kaplan
Aug 1, 1984·Artificial Organs·F Villarroel
Apr 1, 1987·Artificial Organs·A J Nicholls
Apr 1, 1987·Artificial Organs·M FriedbergL P Nielsen
Apr 1, 1987·Artificial Organs·M ForêtD Cordonnier
Nov 24, 1984·British Medical Journal·M M PlattsD C Bartolo
May 10, 1986·British Medical Journal·A J Nicholls
Jun 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M H Mokrzycki, A A Kaplan
Dec 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J M Lazarus, W F Owen
Jun 23, 2009·Diabetic Medicine : a Journal of the British Diabetic Association·F BayraktarA Comlekci
Sep 1, 1985·The Journal of Allergy and Clinical Immunology·L C GrammerR Patterson
Oct 19, 2019·BMC Nephrology·Damien AshbyMartin Wilkie
Nov 6, 1986·The New England Journal of Medicine·S F LeitmanM A Kaliner

Related Concepts

Anaphylaxis
Blood
Bronchial Spasm
Ethylene Oxide
Hemodialysis
Plasmapheresis
Ultrafiltration
Urticaria

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.