PMID: 591116Jan 1, 1977

Anaphylactoid responses in rats

International Archives of Allergy and Applied Immunology
G B West

Abstract

The relative activities of dextran, mannan and ovomucoid as agents inducing anaphylactoid responses in rats vary with the route of injection, mannan being the most active especially by the intradermal route. All of these responses are potentiated by pretreatment with insulin and inhibited by glucose. Carrageenan and concanavalin A are also active but only by the subcutaneous route. Whereas the concanavalin A response is potentiated by insulin, that of carrageenan is reduced. There are therefore at least three classes of agents capable of inducing anaphylactoid responses in rats.

Citations

Mar 1, 1985·Pharmacology, Biochemistry, and Behavior·P Heyward, G Eisenhofer

Related Concepts

Anaphylaxis
lambda-Carrageenan
Concanavalin A
Saviosol
Intradermal Injection
Injections, Intraperitoneal
Subcutaneous Injections
Novolin
Mannans
Ovomucin

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.