Anaphylaxis after hamster bites--identification of a novel allergen

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
D L LimK Y Chua

Abstract

Hamsters are popular household pets and anaphylaxis after their bites have described. However, the putative allergen has not been identified. This study was conducted to identify the allergen causing dwarf hamster (Phodopus sungoris) bite-induced anaphylaxis. Two children with hamster bite-induced anaphylaxis were enrolled. They both had negative results to skin testing and specific IgE to hamster epithelium. However, they were both allergic to Dermatophagoides pteronyssinus (Der p). Identification of the putative IgE-binding allergens from the hamster saliva was performed using immunoblot analysis. A specific IgE-binding component at 21 kD in the hamster saliva was identified. ELISA inhibition tests showed partial inhibition with Der p. The putative allergen from the hamster saliva causing dwarf hamster-induced anaphylaxis was identified. Possible cross-reactivity with Der p was demonstrated. Further studies will be needed to identify the exact nature and function of this allergen.

References

Mar 29, 2002·Contact Dermatitis·Akiko TomitakaKayoko Matsunaga
Aug 8, 2002·Current Allergy and Asthma Reports·Wanda Phipatanakul
Aug 23, 2002·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·F C YiB W Lee

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Citations

Jul 14, 2012·Current Allergy and Asthma Reports·Christiane HilgerFrancois Hentges
Oct 8, 2014·Annales de dermatologie et de vénéréologie·D BrajonA Barbaud
May 31, 2011·Allergologia et immunopathologia·V Marenco-ArellanoA Iglesias-Cadarso
Feb 7, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·G Dutau, F Rancé
Nov 5, 2008·The Journal of Allergy and Clinical Immunology·Joshua F Phillips, Richard F Lockey
Nov 13, 2007·The Journal of Emergency Medicine·John H KlotzJacob L Pinnas
Jun 23, 2005·Allergy·G GuidaG Rolla
Mar 11, 2015·Journal of Medical Microbiology·Claude M NagamineJames G Fox
Sep 14, 2011·International Archives of Allergy and Immunology·J A TorresJ Sastre
Feb 18, 2018·Current Allergy and Asthma Reports·Gregg M Stave
Aug 11, 2017·Journal of Occupational and Environmental Medicine·Gregg M StaveDennis J Darcey

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