Anaphylaxis to artesunate?

Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
S K DubeD K Singh

Abstract

Artesunate, an artemissin derivative is a highly efficacious and relatively safe antimalarial agent. Common adverse reactions to artemissin derivatives are nausea, vomiting, anorexia and dizziness. More serious but less-frequent toxic effects of artesunate use are neutropenia, anemia, hemolysis, elevated liver enzymes and severe allergic reactions. However, anaphylactic reaction to artesunate is a rare entity. Here, we report a case of anaphylaxis to parenteral artesunate and its successful management in a female patient to whom intravenous artesunate was administered during surgery under general anesthesia.

References

Sep 27, 2000·Anesthesia and Analgesia·M BlasE B Lobato
Mar 7, 2002·British Journal of Anaesthesia·M C LaxenaireUNKNOWN Groupe d'Etudes des Réactions Anaphylactoïdes Peranesthésiques
Feb 25, 2003·American Journal of Respiratory and Critical Care Medicine·Nicholas J White
Oct 23, 2003·Anesthesia and Analgesia·David L Hepner, Mariana C Castells
Aug 30, 2005·Lancet·Arjen DondorpUNKNOWN South East Asian Quinine Artesunate Malaria Trial (SEAQUAMAT) group
Apr 25, 2008·The New England Journal of Medicine·Philip J Rosenthal

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Citations

Dec 10, 2013·Pharmacology & Therapeutics·Wanxing Eugene HoW S Fred Wong
Jul 15, 2015·International Journal of Immunopathology and Pharmacology·F MoriM de Martino
Dec 30, 2014·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Tejas K PatelC B Tripathi
Jan 25, 2014·Annual Review of Political Science·Melani Cammett, Pauline Jones Luong
Jul 19, 2020·International Journal of Molecular Sciences·Axelle Septembre-MalaterrePhilippe Gasque

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