Anatomic validation of left ventricular mass estimates from clinical two-dimensional echocardiography: initial results

Circulation
N ReichekK T Weber

Abstract

We performed a prospective anatomic validation study to determine the accuracy of left ventricular (LV) mass estimates from clinical two-dimensional echocardiographic (2-D echo) studies. In 21 subjects, antemortem 2-D echo LV mass determinations were compared with anatomic LV weight by postmortem chamber dissection. Major cardiac diagnoses included anatomic LV aneurysm in four, status post aneurysmectomy in one, transmural myocardial infarction in seven, congestive cardiomyopathy in five, rheumatic mitral disease in two, chronic severe mitral or aortic regurgitation in three, amyloid heart in two, and normal heart in three. Marked right-heart dilatation was present in 11 patients and LV thrombus in four. Regression equations derived in vitro for each 2-D echo instrument were used to correct LV mass estimates based on a short-axis, area-length method: uncorrected LV mass = 1.055 x k x 5/6 (AtLt - AcLc) + b, where At = total short-axis LV image area at the high papillary muscle level, Lc = endocardial LV length, k = an instrument-specific regression slope and b = an instrument-specific intercept. LV mass by 2-D echo correlated extremely well with actual LV weight (r = 0.93 slope = 0.85, SEE = 31 g, range 77-454 g). In contrast, M...Continue Reading

References

Feb 1, 1967·The American Journal of Cardiology·J W KennedyH T Dodge
Jul 1, 1981·The American Journal of Physiology·J S JanickiF J Geheb

❮ Previous
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Citations

Oct 1, 1990·Clinical Cardiology·T Ishizuka, N Furuya
Jan 1, 1992·Clinical Cardiology·D Georgiou, B H Brundage
Jan 1, 1985·International Journal of Cardiac Imaging·N B Schiller
Jan 1, 1987·Cardiovascular and Interventional Radiology·D J Skorton, S M Collins
Jul 1, 1994·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·M S Verani
Feb 16, 1987·Life Sciences·I WakabayashiK Nagai
Jan 1, 1988·Life Sciences·H T MillerS Harwell
Jan 1, 1992·Life Sciences·P KarczewskiJ Schrader
Jan 1, 1995·Life Sciences·S Das, K N Kumar
Jun 30, 1995·International Journal of Cardiology·J MayetS A Thom
Sep 1, 1989·Journal of the American College of Cardiology·H W CollinsB F Byrd
Feb 1, 1989·Journal of the American College of Cardiology·P S DouglasN Reichek
Mar 1, 1990·Journal of the American College of Cardiology·E Z FismanJ J Kellermann
Oct 1, 1991·Journal of the American College of Cardiology·E RoigB H Brundage
Jan 1, 1992·Journal of the American College of Cardiology·M D TischlerJ D Parker
Apr 1, 1993·Journal of the American College of Cardiology·E Di SegniZ Vered
Aug 1, 1994·Journal of the American College of Cardiology·G A Mensah, B F Byrd
Mar 5, 2004·International Journal of Cardiology·Franz C AepfelbacherAndrew J Burger
Jul 30, 1999·American Heart Journal·M HalleJ Keul
Jul 1, 1987·The Annals of Thoracic Surgery·P S DouglasN Reichek
Nov 15, 2002·Transplantation Proceedings·A TürkmenM S Sever
Dec 1, 1984·Journal of the American College of Cardiology·R B DevereuxJ H Laragh
May 1, 1984·Journal of the American College of Cardiology·I P PanidisP Kalman
May 1, 1985·Journal of the American College of Cardiology·J F RenA S Iskandrian
Nov 1, 1985·Journal of the American College of Cardiology·B F ByrdN B Schiller
Jul 1, 1986·Journal of the American College of Cardiology·M S FlorentineD J Skorton

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Next ❯

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