Anatomical and immunohistochemical characteristics of the prostate gland in the greater cane rat (Thryonomys swinderianus)

Anatomia, histologia, embryologia
A O AdebayoB O Oke

Abstract

This study examined the morphology and immunohistochemical features of the prostate gland in 15 captive-reared male greater cane rat of known reproductive and medical history. Samples of the glands were taken after gross examination and routinely prepared for both histological and ultrastructural analysis. Immunohistochemistry was also carried out on paraffin-embedded sections of the glands using rabbit polyclonal antibodies against oestrogen receptors (ERα and ERβ) and mouse monoclonal antibody for the progesterone receptor (PR). The prostate, which constitutes 0.04% of the body weight, was a paired, lobulated, brownish gland having three left and four right lobes that partly cover the pelvic urethra. Based on the amount and arrangement of the secretory epithelial folding and relative to their distances to the urethra, two histological zones, the central and peripheral, were identified. However, the epithelium of both zones was lined by predominantly simple cuboidal cells with occasional basal cells. The main ultrastructural features of these cuboidal cells were the presence of several nuclear pores on the nucleus, moderately well-developed, short microvilli and bleb-like apical projections, as well as inter-cellular lacunae s...Continue Reading

References

Aug 1, 1991·Biology of Reproduction·N HayashiG R Cunha
Jan 1, 1990·Biology of Reproduction·R M BrennerM C McClellan
Jan 1, 1982·The Prostate·C J JesikC Lee
Jan 1, 1981·The Prostate·J E McNeal
Jan 1, 1995·International Urology and Nephrology·V L Kumar, P K Majumder
May 8, 2000·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·C Wendell-Smith
Jun 1, 1960·The Journal of Biophysical and Biochemical Cytology·D BRANDES, A PORTELA
May 20, 2005·Laboratory Animals·A HarmelinO Brenner
Feb 9, 2007·Archives of Histology and Cytology·Ryusuke YoshidaYuzo Ninomiya
Mar 3, 2009·Annals of the New York Academy of Sciences·Stuart J Ellem, Gail P Risbridger
Sep 22, 2009·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Kathleen M ColegroveLinda J Lowenstine
Feb 4, 2010·Arquivos brasileiros de endocrinologia e metabologia·Maria Fatima Magalhães LazariCatarina Segreti Porto
Oct 12, 2010·Biology of Reproduction·Avenel JosephRex A Hess
Nov 13, 2010·Folia Histochemica Et Cytobiologica·Sylwia Słuczanowska-GłąbowskaDariusz Gącarzewicz
Jan 26, 2012·Environmental Health Perspectives·Vickie R WalkerKenneth S Korach
Feb 8, 2013·Journal of Cellular and Molecular Medicine·Lara S CorradiSebastião R Taboga

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