PMID: 25774094Mar 17, 2015Paper

Anatomical, functional and molecular biomarker applications of magnetic resonance neuroimaging

Future Neurology
Christina H Liu

Abstract

MRI and magnetic resonance spectroscopy (MRS) along with computed tomography and PET are the most common imaging modalities used in the clinics to detect structural abnormalities and pathological conditions in the brain. MRI generates superb image resolution/contrast without radiation exposure that is associated with computed tomography and PET; MRS and spectroscopic imaging technologies allow us to measure changes in brain biochemistry. Increasingly, neurobiologists and MRI scientists are collaborating to solve neuroscience problems across sub-cellular through anatomical levels. To achieve successful cross-disciplinary collaborations, neurobiologists must have sufficient knowledge of magnetic resonance principles and applications in order to effectively communicate with their MRI colleagues. This review provides an overview of magnetic resonance techniques and how they can be used to gain insight into the active brain at the anatomical, functional and molecular levels with the goal of encouraging neurobiologists to include MRI/MRS as a research tool in their endeavors.

References

Jun 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·K K KwongR Turner
Aug 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Jan H Ardenkjaer-LarsenKlaes Golman
May 4, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christina H LiuAlex J de Crespigny
Nov 25, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Joseph B MandevilleJohn J A Marota
Aug 27, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·R Grant SteenJeffrey A Lieberman
Jan 20, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christina H LiuPhilip K Liu
Sep 11, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Daniel A HamstraBrian D Ross
Mar 29, 2008·AJNR. American Journal of Neuroradiology·A R DeiblerJ A Maldjian
Apr 23, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Phillip Zhe SunA Gregory Sorensen
Dec 26, 2008·Neurology·Akram BakkourBradford C Dickerson
Feb 4, 2009·Neoplasia : an International Journal for Oncology Research·Anwar R PadhaniPeter L Choyke
Feb 4, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Meredith MetcalfDaniel Pelletier
Mar 20, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christina H LiuPhilip K Liu
Jun 9, 2009·Neurobiology of Aging·R RupsinghR Bartha
Aug 28, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christina H LiuPhilip K Liu
Feb 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·Bharat B BiswalMichael P Milham
Jun 24, 2010·Neurobiology of Aging·Duygu TosunUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Sep 11, 2010·Acta Radiologica·Ileana HancuRobert E Lenkinski
Oct 1, 2010·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·T A G M Huisman
Dec 25, 2010·European Radiology·Frederik BarkhofMike P Wattjes
Mar 10, 2011·Annals of Neurology·Rick C HelmichIvan Toni
Jan 1, 2008·Biomedical Imaging and Intervention Journal·D MoratalMe Brummer
Jun 15, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rolf PohmannD Z Balla
Aug 25, 2011·Neurobiology of Aging·Maja A A BinnewijzendFrederik Barkhof
Sep 29, 2011·NeuroImage·Peter Jezzard
Nov 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Robert M KoffieTara L Spires-Jones
Nov 19, 2011·Stroke; a Journal of Cerebral Circulation·Lynne V GauthierGitendra Uswatte
Dec 14, 2011·Topics in Magnetic Resonance Imaging : TMRI·Michael M ZeinehRoland Bammer
Dec 27, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Christina H LiuPhilip K Liu
Jan 21, 2012·Neuro-degenerative Diseases·Margherita CavalieriReinhold Schmidt

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Citations

Jan 30, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·H BlascoP Corcia
Jun 24, 2017·Biofabrication·Tuğrul Tolga DemirtaşMenemşe Gümüşderelioğlu
Nov 7, 2017·Cerebral Cortex·Carmen Perez-LasoAntonio Guillamon

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