Anatomoclinical study of ovarian cancers in patients with history of hysterectomy for benign pathology

Journal de gynécologie, obstétrique et biologie de la reproduction
C CornouChristophe Pomel

Abstract

To establish the various anatomoclinical characteristics of ovarian cancer in patients with a history of hysterectomy for benign disease. This is a comparative, retrospective, monocentric and descriptive study, carried out at the Centre of Jean-Perrin in patients with ovarian cancer between 2005 and 2014 and with a history of hysterectomy for benign disease. Each patient was paired with a non-hysterectomy patient with ovarian cancer. The two populations were matched 1 to 5, based on their age at diagnosis and their FIGO stage. During the period of the study, 249 patients were operated for de novo ovarian neoplasia, 43 patients had a history of hysterectomy (group 1) and 206 remaining patients represented the control group (group 2). There was no difference in overall survival and disease-free survival between the two subpopulations of patients (P=0.59 and P=0.38). On CT-scan assessment, the lymph node involvement risk was greater than 2.6 in the group of patients with hysterectomy (P=0.00038). Peritoneal Cancer Index scores of the two subgroups of populations were comparable, there were an average of 13.65 for group 1 versus 12.31 for group 2 (P=0.28). The rate of rectosigmoid resection was higher in group 1: 48.6% versus 32.9%...Continue Reading

References

Apr 1, 1994·American Journal of Obstetrics and Gynecology·A L Herbst
Sep 2, 1999·Journal of the National Cancer Institute·R B Ness, C Cottreau
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·F. Di Re, G. Baiocchi
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert E BristowF J Montz
Feb 1, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A-A K TentesK Avgidou
Aug 2, 2003·Journal of the American College of Surgeons·Philippe MoriceDamienne Castaigne
May 3, 2005·Gynecologic Oncology·Francesca ChiaffarinoCarlo La Vecchia
Jan 27, 2007·The American Journal of Surgical Pathology·David W KindelbergerChristopher P Crum
Sep 2, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Joseph W CarlsonChristopher P Crum
Feb 16, 2010·The American Journal of Surgical Pathology·Robert J Kurman, Ie-Ming Shih
Jul 3, 2010·American Journal of Obstetrics and Gynecology·Anna FagottiGiovanni Scambia
Sep 8, 2010·The New England Journal of Medicine·Ignace VergoteUNKNOWN NCIC Clinical Trials Group
Dec 1, 2008·Journal de chirurgie·D Salet-Lizée, S Alsary
Dec 1, 2008·Journal de chirurgie·D Salet-Lizée, S Alsary
Jul 31, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Susan J JordanPenelope M Webb
Jan 28, 2014·Obstetrics and Gynecology·John K ChanLaurel A Habel

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