Jan 27, 2009

Anatomy and development of the nervous system of Nematostella vectensis, an anthozoan cnidarian

Developmental Neurobiology
Heather Q MarlowMark Q Martindale

Abstract

Nematostella vectensis, an anthozoan cnidarian, whose genome has been sequenced and is suitable for developmental and ecological studies, has a complex neural morphology that is modified during development from the larval to adult form. N. vectensis' nervous system is a diffuse nerve net with both ectodermal sensory and effector cells and endodermal multipolar ganglion cells. This nerve net consists of several distinct neural territories along the oral-aboral axis including the pharyngeal and oral nerve rings, and the larval apical tuft. These neuralized regions correspond to expression of conserved bilaterian neural developmental regulatory genes including homeodomain transcription factors and NCAMs. Early neurons and stem cell populations identified with NvMsi, NvELAV, and NvGCM, indicate that neural differentiation occurs throughout the animal and initiates prior to the conclusion of gastrulation. Neural specification in N. vectensis appears to occur through an independent mechanism from that in the classical cnidarian model Hydra.

  • References70
  • Citations86

References

  • References70
  • Citations86

Citations

Mentioned in this Paper

Ganglion Cell
Coral
Hydra Polyps
Science of Morphology
Entire Nervous System
Neurons
Nematostella vectensis
Ectodermal
Immunocytochemistry
Cnidaria

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