Ancestry-related assortative mating in Latino populations.

Genome Biology
Neil RischEsteban González Burchard

Abstract

While spouse correlations have been documented for numerous traits, no prior studies have assessed assortative mating for genetic ancestry in admixed populations. Using 104 ancestry informative markers, we examined spouse correlations in genetic ancestry for Mexican spouse pairs recruited from Mexico City and the San Francisco Bay Area, and Puerto Rican spouse pairs recruited from Puerto Rico and New York City. In the Mexican pairs, we found strong spouse correlations for European and Native American ancestry, but no correlation in African ancestry. In the Puerto Rican pairs, we found significant spouse correlations for African ancestry and European ancestry but not Native American ancestry. Correlations were not attributable to variation in socioeconomic status or geographic heterogeneity. Past evidence of spouse correlation was also seen in the strong evidence of linkage disequilibrium between unlinked markers, which was accounted for in regression analysis by ancestral allele frequency difference at the pair of markers (European versus Native American for Mexicans, European versus African for Puerto Ricans). We also observed an excess of homozygosity at individual markers within the spouses, but this provided weaker evidence...Continue Reading

References

Jan 1, 1990·Behavior Genetics·C T NagoshiG P Danko
Oct 1, 1985·Journal of Biosocial Science·A TrachtenbergF J Da Rocha
Jan 1, 1969·Human Heredity·N Yasuda
Aug 1, 1969·Scientific American·L L Cavalli-Sforza
Nov 1, 1965·Annals of Human Genetics·H KriegerN Yasuda
Oct 1, 1982·Archives of General Psychiatry·K R Merikangas
Jul 1, 1983·Journal of Biosocial Science·R M MalinaB B Little
Jun 1, 1981·American Journal of Physical Anthropology·A R FrisanchoA Way
Oct 1, 1994·Journal of Biosocial Science·A Sánchez-Andrés, M S Mesa
Jan 1, 1964·Cold Spring Harbor Symposia on Quantitative Biology·N E MORTON
Nov 18, 2003·American Journal of Respiratory and Critical Care Medicine·Esteban González BurchardUNKNOWN Genetics of Asthma in Latino Americans (GALA) Study
Feb 20, 2004·Twin Research : the Official Journal of the International Society for Twin Studies·Yoon-Mi Hur
Nov 1, 2005·American Journal of Public Health·Esteban González BurchardNeil Risch
Nov 12, 2005·Human Genetics·Shweta ChoudhryUNKNOWN Genetics of Asthma in Latino Americans GALA Study
Sep 16, 2006·American Journal of Respiratory and Critical Care Medicine·Shweta ChoudhryNeil J Risch
Jun 19, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Rona YaegerAndrew K Joe

❮ Previous
Next ❯

Citations

Sep 30, 2010·Human Molecular Genetics·Brenna M HennCarlos D Bustamante
Jun 15, 2011·Annals of Human Genetics·Lynda D LisabethJeffrey C Long
Nov 25, 2011·Annals of Human Genetics·Ronnie SebroNeil J Risch
Dec 3, 2009·Genome Biology·Andrew S Burrell, Todd R Disotell
Nov 19, 2013·PLoS Genetics·Andrés Moreno-EstradaCarlos D Bustamante
Apr 17, 2012·PloS One·Sergio AvenaLaura Fejerman
Oct 5, 2011·Genetics·Paul Verdu, Noah A Rosenberg
Oct 21, 2015·Proceedings of the National Academy of Sciences of the United States of America·James Y ZouNoah Zaitlen
Jun 7, 2011·Theoretical Population Biology·Simina M Boca, Noah A Rosenberg
Oct 30, 2010·Genetic Epidemiology·Hua TangStephanie J London
Apr 5, 2013·American Journal of Physical Anthropology·Jada Benn TorresRick Kittles
May 12, 2012·Autoimmune Diseases·Paola Cruz-TapiasJuan-Manuel Anaya
Jun 15, 2015·Bioinformatics·James Y ZouSriram Sankararaman
Jul 1, 2015·Proceedings of the National Academy of Sciences of the United States of America·Fernanda S G KehdyUNKNOWN Brazilian EPIGEN Project Consortium
Oct 9, 2014·European Journal of Human Genetics : EJHG·Thiago Magalhães da SilvaRonald E Blanton
Apr 22, 2016·Birth Defects Research. Part A, Clinical and Molecular Teratology·Suzan L CarmichaelGary M Shaw
Jul 4, 2012·American Journal of Human Genetics·Timothy ThorntonNeil Risch
Jun 4, 2013·The Journal of Urology·Suzan L CarmichaelGary M Shaw
May 6, 2015·PloS One·Rafael Parra-MedinaJuan-Manuel Anaya
Oct 1, 2016·Current Opinion in Genetics & Development·Kaustubh AdhikariAndrés Ruiz-Linares
May 26, 2017·American Journal of Physical Anthropology·Bridget F B Algee-Hewitt
Jul 5, 2017·American Journal of Human Biology : the Official Journal of the Human Biology Council·José Ángel Cahua-PabloEugenia Flores-Alfaro
Nov 18, 2017·Scientific Reports·Xiaoyin LiXiaofeng Zhu
Nov 14, 2017·American Journal of Physical Anthropology·Jessica M Gross
Mar 21, 2019·Proceedings. Biological Sciences·Claire Dandine-RoullandRaphaëlle Chaix
Feb 10, 2019·Pediatric Diabetes·Marcia PuñalesBalduino Tschiedel
Jun 22, 2017·American Journal of Physical Anthropology·Bridget F B Algee-Hewitt
Nov 11, 2014·PloS One·Guang GuoThomas Randall
Apr 17, 2019·Nature Human Behaviour·Loic YengoPeter M Visscher
Sep 30, 2017·American Journal of Human Biology : the Official Journal of the Human Biology Council·Susanne Huber, Martin Fieder
May 21, 2019·Frontiers in Genetics·Emily T NorrisI King Jordan
Apr 7, 2017·PLoS Genetics·Ronnie SebroNeil J Risch
Apr 25, 2020·American Journal of Human Biology : the Official Journal of the Human Biology Council·Jimena FritzHector Lamadrid-Figueroa
Jul 23, 2020·Politics and the Life Sciences : the Journal of the Association for Politics and the Life Sciences·Tomás Cabeza de BacaVanessa Smith-Castro

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Methods Mentioned

BETA
genotyping
chip
PCR

Software Mentioned

TYPER
Structure
PLINK

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