Anchored cAMP signaling: onward and upward - a short history of compartmentalized cAMP signal transduction

European Journal of Cell Biology
F Donelson Smith, John D Scott

Abstract

Intracellular signal transduction pathways require a high degree of spatial and temporal resolution in order to deliver the appropriate outputs. Specific signaling mediated by the ubiquitous second messenger cAMP and its effector, the cAMP-dependent protein kinase (PKA), is governed by the spatial organization of different pathway components by A-kinase anchoring proteins (AKAPs). This review discusses the history and future of anchored cAMP signaling pathways.

References

Jan 13, 1978·Science·P Greengard
Sep 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·E M Ross, A G Gilman
Feb 21, 1991·Nature·S R AdamsR Y Tsien
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J L BenovicR J Lefkowitz
Mar 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·M D UhlerG S McKnight
Nov 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·S M LohmannU Walter
Jul 22, 1983·Science·T S Ingebritsen, P Cohen
Mar 1, 1993·Trends in Biochemical Sciences·S S TaylorM J Zoller
Oct 23, 1997·Proceedings of the National Academy of Sciences of the United States of America·L J HuangS S Taylor
Mar 13, 1999·Nature Structural Biology·M G NewlonP A Jennings
Jan 6, 2000·Nature Cell Biology·M ZaccoloT Pozzan
Mar 14, 2000·Current Opinion in Cell Biology·S H Soderling, J A Beavo
Aug 3, 2000·Frontiers in Bioscience : a Journal and Virtual Library·B S Skalhegg, K Tasken
Mar 27, 2001·Annual Review of Pharmacology and Toxicology·S F Steinberg, L L Brunton
Apr 4, 2001·The Journal of Biological Chemistry·K A TaskénK Taskén
Dec 26, 2001·Chemical Reviews·D A JohnsonS S Taylor
Dec 26, 2001·Proceedings of the National Academy of Sciences of the United States of America·J ZhangR Y Tsien
Aug 16, 2002·Nature·Sharon EdenMarc W Kirschner
Oct 9, 2002·Trends in Biochemical Sciences·Gerard ManningSucha Sudarsanam
Nov 26, 2002·Nature Cell Biology·Scott H SoderlingJohn D Scott
Aug 5, 2003·The Journal of Biological Chemistry·Mikaela GrönholmOlli Carpén
Feb 7, 2004·The EMBO Journal·Anika SteffenTheresia E B Stradal
Apr 20, 2004·Journal of Cell Science·Michele K Dougherty, Deborah K Morrison
Aug 18, 2004·Nature Biotechnology·Blagoy BlagoevMatthias Mann
Sep 24, 2004·Molecular Cell·Graeme K CarnegieJohn D Scott
Oct 16, 2004·Annual Review of Genomics and Human Genetics·Carmen L de Hoog, Matthias Mann
Oct 18, 2005·Nature Cell Biology·Naoto HoshiJohn D Scott

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Citations

Apr 23, 2013·Pflügers Archiv : European journal of physiology·Kavisha AroraAnjaparavanda P Naren
Sep 21, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ting NieTed Abel
Feb 1, 2008·Experimental Eye Research·Oscar A CandiaLawrence J Alvarez
Oct 29, 2009·Human Mutation·Paula L HedleyMichael Christiansen
Mar 26, 2009·IUBMB Life·Graeme K CarnegieJohn D Scott
Jan 30, 2013·Biological Reviews of the Cambridge Philosophical Society·Juana M Gancedo
Jun 20, 2012·Proteomics·Pascal Braun, Anne-Claude Gingras
May 27, 2008·Journal of Dental Research·S WongkhanteeP Pavasant
Dec 7, 2017·Frontiers in Microbiology·Poonguzhali SelvarajNaweed I Naqvi
Jan 18, 2008·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Kacper A WojtalSven C D van Ijzendoorn
May 26, 2007·The Journal of Pharmacology and Experimental Therapeutics·Matthew L Bilodeau, Heidi E Hamm
Apr 4, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Shuang LiangGeorge Hajishengallis

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