Androgen receptor and follicle-stimulating hormone receptor in the pig ovary during the follicular phase of the estrous cycle

Molecular Reproduction and Development
H Cárdenas, W F Pope

Abstract

Follicle-stimulating hormone (FSH) is an important regulator of follicular development. Some effects of FSH on ovarian follicles might be enhanced by androgens. The main objectives of the present study were to examine expression of the androgen receptor (AR) and FSH receptor (FSHR) in late developing follicles in pigs. Ovaries were collected from gilts on days 13, 15, 17, and 19 of the estrous cycle (day 0 = first day of estrus, n = 4 gilts/day), a period coincident with the follicular phase. One ovary was processed for immunohistochemistry (IHC) of AR. Samples of surface wall from the largest follicles (4-5 per gilt) were dissected from the other ovary, pooled and processed for determination of AR and FSHR mRNAs using reverse transcription-polymerase chain reaction (RT-PCR). Intense AR immunostaining was present in nuclei of granulosa cells of preantral and antral follicles. AR immunoreactivity was also present in the nuclei of oocytes. Weak staining for AR was observed in cells of the theca interna, ovarian surface epithelium, and in most cells of the ovarian stroma. Relative amounts of immunoreactive AR in granulosa cells of late developing follicles, or small antral follicles (< 2 mm), did not differ between days 13, 15, 17...Continue Reading

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Citations

Feb 6, 2009·Molecular Human Reproduction·Mo LiQing-Yuan Sun
Apr 4, 2003·Biology of Reproduction·C J CorbinA J Conley
Jul 23, 2004·Biology of Reproduction·Kara L BrittJock K Findlay
Apr 22, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·Dieter SchamsBajram Berisha
Jan 3, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Jennifer L JuengelKenneth P McNatty
Feb 8, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·Disha PantAnna T Grazul-Bilska
Feb 27, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·H CárdenasW F Pope
Jul 10, 2014·ISRN Obstetrics and Gynecology·Catiele Garcia GervásioAna Carolina Japur de Sá Rosa-E-Silva
Jul 20, 2014·The Journal of Endocrinology·Hen PrizantAritro Sen
Aug 1, 2015·Molecular Reproduction and Development·Jingjie XuHaibin Kuang
May 8, 2007·Acta histochemica·Małgorzata BurekMaria Słomczyńska
Jul 21, 2010·Reproduction in Domestic Animals = Zuchthygiene·M DurlejM Slomczynska
May 19, 2004·Acta histochemica·Martin StefflW M Werner M Amselgruber
Sep 24, 2004·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Malin BoströmJoseph W DePierre
Nov 16, 2007·Biology of Reproduction·K A WaltersD J Handelsman
Jan 18, 2008·Reproduction in Domestic Animals = Zuchthygiene·M SłomczyńskaM Koziorowski
Oct 11, 2007·Molecular Reproduction and Development·Gab Sang LeeSang Hwan Hyun
Jan 15, 2016·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Erin L DamsteegtP Mark Lokman
Apr 22, 2009·Molecular Reproduction and Development·Radek ProcházkaAlzbeta Mlynarcíková

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