Androgenic adult granulosa cell tumor in a teenager: a case report and review of the literature

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
C KabacaS Cesur

Abstract

The clinicopathologic findings of the third case of androgenic adult granulosa cell tumor in patients younger than 15 years was presented and discussed in the light of the literature. A patient complaining of secondary amenorrhea and hirsutism with elevated levels of plasma total testosterone, dehydroepiandrosterone sulfate, free androgen index and serum inhibin A, and a left ovarian septated, cystic mass was admitted to the hospital. The inhibin A level was within normal levels in the first month postoperatively. Inhibin A could be a tumor marker of utmost importance particularly in patients with androgenic or hyperestrogenic symptoms, especially in cases where benign criteria are abundant such as young age, nonincreased levels of classic tumor markers, and ultrasonographic appearance without any suspicion of malignancy.

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Citations

Sep 26, 2012·ISRN Obstetrics and Gynecology·Rani KanthanSelliah Kanthan
Dec 9, 2008·Fertility and Sterility·Satin S PatelBruce R Carr
Apr 4, 2007·European Journal of Radiology·Yumiko Oishi TanakaManabu Minami
Feb 23, 2012·The Journal of Obstetrics and Gynaecology Research·Tomoko AdachiMasao Nakabayashi
Jan 27, 2017·Molecular and Clinical Oncology·Dorottya BúsGyörgy Vajda

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