PMID: 16623112Apr 21, 2006Paper

Anemia in kidney diseases as a cardiovascular risk factor

Przegla̧d lekarski
Michał Myśliwiec, Grzegorz Zalewski

Abstract

Cardiovascular mortality is increased in chronic kidney diseases. Patients' survival correlates with hemoglobin concentration. Anemia significantly affects cardiovascular system, especially the heart. Heart failure, anemia and chronic renal failure are mutually related. Recently, cardio-renal-anemia syndrome (CRAS) was defined. Iron replacement and EPO treatment can break the pathogenetic circle of events leading to heart failure. Increased hemoglobin concentration can also induce a positive impact on renal function. Early diagnosis and correction of anemia has a substantial role in prophylaxis of left ventricular hypertrophy in patients with chronic renal insufficiency.

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