Anemia Increases Mortality After Open or Endovascular Treatment in Patients with Critical Limb Ischemia: A Retrospective Analysis

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
A VelescuM Mellado

Abstract

Pre-operative anemia has been associated with increased post-operative morbidity and mortality in elective cardiac surgery, but its association with post-operative mortality after open or endovascular surgery for critical limb ischemia (CLI) is not well established. The aim of this study was to evaluate the relationship between pre-operative anemia and mortality in surgery for CLI. A retrospective study of 403 consecutive patients (mean age = 73; 73% male) undergoing open (n = 191, 47%) or endovascular (n = 212, 53%) surgery for CLI between 2005 and 2013 was performed. Neither redo revascularization procedures (ipsilateral or contralateral) nor acute limb ischemia patients were included as new cases. The best cut off (receiver operating characteristic curve) that related pre-operative hemoglobin to mortality was 10 g/dL. The immediate (in hospital or < 30 days) mortality rate was 8% (32 patients), with no significant differences between open and endovascular surgery. Patients with a pre-operative hemoglobin <10 g/dl had a higher immediate mortality rate (17.7% vs. 5.1%), with a risk (OR), adjusted by age and prior myocardial infarction, of 3.9, 95% CI 1.8-8.4 (p = 0.001). The mean follow up of the cohort was 30 months (97% comp...Continue Reading

References

Mar 31, 2004·The American Journal of Medicine·Aryeh ShanderRichard Spence
Jan 1, 1950·Cancer·W J YOUDEN
Jun 2, 2006·Journal of the American Society of Nephrology : JASN·Marcello TonelliAmit X Garg
Jun 15, 2007·JAMA : the Journal of the American Medical Association·Wen-Chih WuPeter D Friedmann
Jul 11, 2007·Circulation·Alexander KulierUNKNOWN Ischemia Research and Education Foundation
Mar 1, 2011·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M Vega de CénigaA Barba
Jun 18, 2014·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·I DesormaisP Lacroix

❮ Previous
Next ❯

Citations

Mar 13, 2019·JAMA : the Journal of the American Medical Association·Markus M MuellerUNKNOWN ICC PBM Frankfurt 2018 Group
May 25, 2018·International Angiology : a Journal of the International Union of Angiology·Mireia MartínezAlbert Clarà
Jan 6, 2021·European Journal of Anaesthesiology·Carolien S E BulteUNKNOWN and the Clinical Trial Network of the European Society of Anaesthesiology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.