Anesthetic and cardiopulmonary effects of intramuscular morphine, medetomidine, ketamine injection in dogs

Veterinary Anaesthesia and Analgesia
Yukie UeyamaW W Muir

Abstract

To determine the quality and duration of anesthesia and the cardiopulmonary effects of a morphine, medetomidine, ketamine (MMK) combination administered intramuscularly (IM) to dogs. Descriptive injectable anesthetic protocol evaluation. Eight intact adult Beagle dogs: five males, three females. The electrocardiogram, heart rate, direct arterial blood pressure, and core body temperature were monitored in eight chronically instrumented dogs. Each dog received 0.2 mg kg(-1) morphine sulfate, 20 microg kg(-1) medetomidine hydrochloride, and 5 mg kg(-1) ketamine hydrochloride IM. Anesthetic and analgesic effects (clamping the tail and metatarsus) were categorized, and the times to lateral recumbency, orotracheal intubation, extubation, and sternal recumbency were recorded. Respiratory, cardiovascular, temperature, and acid-base variables were recorded 5 minutes before, and 3, 10, 20, 30, 45, 50, and 60 minutes after MMK. Atipamezole, 100 microg kg(-1) IM, was administered 60 minutes after MMK administration and data recorded 10 minutes later. The onset of anesthesia was uneventful and rapid. Time to lateral recumbency was 7.1 +/- 4.1 minutes. The tracheas of four dogs were orally intubated in 5.1 +/- 0.8 minutes. After MMK administ...Continue Reading

References

Jul 1, 1995·Veterinary Surgery : VS·H S de Morais, W W Muir
Jun 1, 1993·Journal of Veterinary Pharmacology and Therapeutics·D SerteynM Lamy
Jun 1, 1997·Zentralblatt für Veterinärmedizin. Reihe A·N TomizawaS Hara
Dec 9, 1998·Veterinary Surgery : VS·B H Pypendop, J P Verstegen
Apr 8, 1999·Clinical Techniques in Small Animal Practice·M M Glowaski, L A Wetmore
Apr 8, 1999·Clinical Techniques in Small Animal Practice·J E Ilkiw
May 29, 2000·Journal of the American Veterinary Medical Association·J C KoR E Mandsager
Sep 26, 2001·The Journal of Small Animal Practice·K J RobinsonP J Cripps
Jun 17, 2004·American Journal of Veterinary Research·Phillip Lerche, William W Muir
Jan 24, 2006·Journal of the American Veterinary Medical Association·Antonio PozziFrancesca Traverso

❮ Previous
Next ❯

Citations

May 3, 2011·Journal of the American Veterinary Medical Association·Michele BarlettaTomohito Inoue
Nov 28, 2014·The Journal of Veterinary Medical Science·Jun TamuraKazuto Yamashita
Jan 1, 2009·Veterinary Anaesthesia and Analgesia

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.