Anesthetic and recovery profiles of lidocaine versus mepivacaine for spinal anesthesia in patients undergoing outpatient orthopedic arthroscopic procedures

Journal of Clinical Anesthesia
J PawlowskiW Scott Jellish

Abstract

To compare isobaric lidocaine and mepivacaine in outpatient arthroscopic surgery. Prospective, randomized, double-blinded study. Ambulatory surgery center affiliated with an academic tertiary-care hospital. 84 adult, ASA physical status 1, 2, and 3 ambulatory patients, age 18-70 years, undergoing arthroscopic knee surgery. Patients were randomized to receive a combination spinal-epidural anesthetic using 80 mg of either isobaric 2% mepivacaine or isobaric 2% lidocaine. Patients also received a femoral 3-in-1 block with 0.5% bupivacaine applied to the affected extremity. Demographic data and level and duration of the block were recorded. The use of supplemental epidural anesthesia was noted along with frequency of bradycardia, hypotension, and episodes of nausea and vomiting. Duration of block and times to ambulation and voiding were recorded. Delayed variables, including fatigue, difficulty urinating, back pain, and transient neurologic symptoms (TNS) were obtained. No demographic differences were noted between groups, and surgical duration was similar. Satisfactory anesthesia was achieved in all cases, with no differences noted in hypotension, bradycardia, nausea, or vomiting. Onset of sensory and motor block was similar. Dura...Continue Reading

References

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Citations

Jan 1, 2014·Advanced Healthcare Materials·Bret D UleryCato T Laurencin
Dec 22, 2016·The Journal of the American Academy of Orthopaedic Surgeons·Charles A GoldfarbRobert H Brophy
Sep 27, 2018·The Journal of Pharmacy and Pharmacology·Jann-Inn TzengYu-Wen Chen
May 16, 2014·Current Opinion in Anaesthesiology·Hillenn Cruz EngKi Jinn Chin
Feb 27, 2017·Journal of Clinical Anesthesia·Bradley H Lee, Matthias Braehler

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