Aneuploidies in embryos and spermatozoa from patients with Y chromosome microdeletions

Fertility and Sterility
Emilia MateuCarmen Rubio

Abstract

In patients with Y chromosome microdeletions and high percentage of numeric chromosome abnormalities detected by fluorescence in situ hybridization on sperm, a high percentage of abnormal embryos was observed compared with oligozoospermic patients without Y chromosome microdeletions, with a significant increase in the percentage of embryos with monosomy X. Differences in fertilization rates between the different patient groups were not observed; however, blastocyst rates were significantly impaired in patients with Y chromosome microdeletions.

Associated Clinical Trials

References

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Citations

Mar 16, 2018·Expert Review of Molecular Diagnostics·Csilla KrauszAntoni Riera-Escamilla
Apr 7, 2018·Nature Reviews. Urology·Csilla Krausz, Antoni Riera-Escamilla
Feb 20, 2018·Reproductive Biology and Endocrinology : RB&E·Stacy Colaco, Deepak Modi
Feb 6, 2019·Biology of Reproduction·Carmen RubioCarlos Simón
Sep 13, 2018·Journal of Assisted Reproduction and Genetics·Stacy Colaco, Denny Sakkas
Jun 20, 2019·Journal of Assisted Reproduction and Genetics·Stacy Colaco, Deepak Modi
May 1, 2017·Human Genetics·C Krausz, E Casamonti

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