Aneuploidy screening: what test should I use?

Obstetrics and Gynecology
Richard L BerkowitzMary E D'Alton

Abstract

Screening for the risk of fetal aneuploidy can be effectively performed in either the first or second trimester. When obtained independently, the interpretation of those data is straightforward. However, the effectiveness of screening can be enhanced by combining studies performed in each trimester in a variety of ways. In this commentary we will define and discuss both the advantages and disadvantages of using integrated, stepwise, sequential or contingency screening for risk assessment of fetal aneuploidy.

References

Jan 1, 1997·Journal of Medical Screening·N J WaldA McGuire
Jul 23, 1999·Prenatal Diagnosis·H S Cuckle, J M van Lith
Jul 31, 2004·Nature Genetics·Gavin Sherlock
Nov 12, 2005·The New England Journal of Medicine·Fergal D MaloneUNKNOWN First- and Second-Trimester Evaluation of Risk (FASTER) Research Consortium

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Citations

Jul 4, 2006·Obstetrics and Gynecology·Natasha ShurSusan J Gross
Mar 5, 2009·Orvosi hetilap·Sándor Gardó

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