PMID: 8601243Apr 1, 1996Paper

Aneurysms due to intimomedial mucoid degeneration

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
A T Abdool-CarrimK Cooper

Abstract

Review management of patients presenting with aneurysms due to intimomedial mucoid degeneration (IMMD). Retrospective analysis. Metropolitan Vascular Service, Departments of Haematology and Pathology, University of Natal. Case records reviewed over an 11 year period. Twenty-two patients were submitted for surgery. All had histological confirmation of disease. All patients were black African (Negro) descent and nineteen were female. Average age was 52 years. Fifteen patients had involvement of descending aorta and seven patients had extra-aortic involvement. Hypertension was noted in half of the patients. Seven patients presented acutely with rupture (4) and ischaemic lower limbs due to dissection (3). Total absence of clot within aneurysm lumen was a distinctive finding on ultrasound, CT-scan and angiography. Treatment followed standard vascular surgical principles. Three patients died following emergency aortic replacement. Three patients developed severe intraoperative bleeding problems following elective aortic aneurysm resection due to primary fibrinolysis. All had normal preoperative coagulation profiles. IMMD is a rare disease affecting the intima and media of vessel wall involving aortic and extra aortic vessels, predomi...Continue Reading

References

Apr 1, 1973·The Journal of Pathology·I SteinerM S Hutt
May 1, 1967·Archives of Internal Medicine·N L FineL Castleman

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Citations

Nov 28, 2001·Postgraduate Medical Journal·W A StalmanY van der Graaf
Oct 28, 2008·Journal of Vascular and Interventional Radiology : JVIR·Jeremy R KatzCharles A Owens
Jan 11, 2011·Journal of Vascular Surgery·Menno H RaberRob J van Det
Aug 26, 2019·Forensic Science, Medicine, and Pathology·Kim WiskottChristelle Lardi
Oct 30, 2019·Journal of Vascular Surgery Cases and Innovative Techniques·Georgios TzavellasApostolos K Tassiopoulos

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