Angina Pectoris and Myocardial Ischemia in the Absence of Obstructive Coronary Artery Disease: Role of Diagnostic Tests

Current Cardiology Reports
Gaetano A Lanza

Abstract

Patients with chest pain and nonobstructive coronary artery disease (NO-CAD) at angiography constitute a heterogeneous population. In most patients with stable exercise-induced chest pain, microvascular angina (MVA) is the likely diagnosis. Some clinical findings and results of diagnostic tests suggest that angina is caused by coronary microvascular (CMV) dysfunction rather than obstructive CAD, but a definitive diagnosis requires demonstration of impaired CMV dilation and/or increased constriction. About 10 % of patients presenting with an acute coronary syndrome also shows NO-CAD at angiography, and CMV constriction can be responsible for the syndrome in a number of cases. Diagnostic tests are not expected to have a prognostic role in patients with stable MVA with normal coronary arteries, due to the excellent prognosis of these patients, whereas their prognostic role in the more general population of NO-CAD patients with chest pain (either stable or acute) needs to be established in adequate studies.

References

Nov 15, 1991·Journal of the American College of Cardiology·P NihoyannopoulosA Maseri
Feb 1, 1991·Journal of the American College of Cardiology·A MaseriT Crake
Nov 1, 1990·Journal of the American College of Cardiology·R O CannonS E Epstein
Jun 1, 1988·The American Journal of Cardiology·R O Cannon, S E Epstein
Sep 1, 1987·The American Journal of Cardiology·E PicanoA L'Abbate
Dec 1, 1986·The American Journal of Cardiology·J C KaskiA Maseri
Dec 1, 1980·Circulation Research·R M Berne
Jun 1, 1983·Journal of the American College of Cardiology·R O CannonS E Epstein
Mar 15, 1995·Journal of the American College of Cardiology·J C KaskiP A Poole-Wilson
Apr 1, 1995·The American Journal of Cardiology·G A LanzaA Maseri
Feb 1, 1996·Journal of the American College of Cardiology·A ElhendyP M Fioretti
Feb 1, 1997·Journal of the American College of Cardiology·A A QuyyumiR O Cannon
Jan 13, 1998·Journal of the American College of Cardiology·V PasceriA Maseri
Jun 27, 1998·Lancet·M MohriA Takeshita
Oct 17, 2001·European Heart Journal·G A LanzaA Maseri
May 30, 2002·Circulation·Nico H J PijlsFrans Van De Vosse
Jun 21, 2002·The New England Journal of Medicine·Jonathan R PantingDudley J Pennell
Jul 10, 2003·American Heart Journal·John F BeltrameJohn D Horowitz
Jun 2, 2004·Journal of Magnetic Resonance Imaging : JMRI·Michael Jerosch-HeroldArthur E Stillman
Jul 6, 2004·Journal of the American College of Cardiology·John F BeltrameJohn D Horowitz
Jan 5, 2005·Journal of the American College of Cardiology·Hisham DokainishUNKNOWN TACTICS-TIMI-18 Investigators
Aug 12, 2006·European Journal of Nuclear Medicine and Molecular Imaging·John O PriorHeinrich R Schelbert
Jan 24, 2007·Heart·Gregory Angelo SguegliaGaetano Antonio Lanza
Feb 26, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrick Meimoun, Christophe Tribouilloy
Jul 9, 2008·Journal of Cardiovascular Medicine·Joseph A DiamondMilena J Henzlova
Nov 6, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fadi AlqaisiKarthik Ananthasubramaniam

❮ Previous
Next ❯

Citations

Mar 31, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Antonio De VitaFilippo Crea
Nov 18, 2018·Interventional Cardiology·Gaetano Antonio LanzaJuan-Carlos Kaski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.