PMID: 11921960Feb 1, 1996Paper

Angioedema due to medication treatment

Nederlands tijdschrift voor tandheelkunde
N M TimmengaA Knol

Abstract

Patients with hypertension can be treated by inhibition of angiotensin-converting enzyme (ACE). A major side-effect of the use of ACE-inhibitors is the development of a life threatening dyspneu by angioedema of oropharyngeal and laryngeal tissue. This severe complication is caused by interaction of ACE-inhibitors with prostaglandin and bradykinin metabolisms. Minor manifestations of angioedema can be followed by severe reactions. It is wise to stop ACE-inhibitors immediately.

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