Angiogenesis in cutaneous disease: part I

Journal of the American Academy of Dermatology
Amy NguyenKristen M Kelly

Abstract

Angiogenesis is an important process in normal physiology and disease pathogenesis. Angiogenesis is controlled in a healthy body by a system of angiogenic growth factors and angiogenesis inhibitors. When angiogenic growth factors are predominantly expressed, blood vessel growth occurs and disease may result. Successful therapies have been developed that target growth factors, their receptors, or the cascade pathways that are activated by growth factor/receptor interactions. There is good evidence that angiogenesis plays an important role in a wide range of cutaneous maladies, and angiogenesis-targeting therapies are playing an increasing role in the management of dermatologic disease. Cutaneous angiogenesis offers an exciting new arena for targeted dermatologic therapeutics. After completing this learning activity, participants should be able to distinguish angiogenic growth factors and inhibitors, recognize angiogenic mediating agents and compare their mechanisms of action, and apply the use of angiogenic mediating agents in clinical and research situations.

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Citations

Apr 10, 2012·Seminars in Oncology·Caroline RobertBasil S Cherpelis
Jan 25, 2011·Seminars in Oncology Nursing·Cathleen M Goetsch
Jun 3, 2011·The Journal of Investigative Dermatology·Hamid R RezvaniFrédéric Mazurier
Feb 27, 2013·Lasers in Surgery and Medicine·Vivian T LaquerKristen M Kelly
Feb 4, 2012·Lasers in Surgery and Medicine·Vivian T LaquerKristen M Kelly
Jul 19, 2015·The American Journal of Pathology·Christopher SchusterAdelheid Elbe-Bürger
Dec 5, 2013·The American Journal of Pathology·Jinqing LiDavid A Gerber
Oct 28, 2015·Lasers in Surgery and Medicine·Thomas D GriffinNazanin Saedi
May 11, 2017·Brazilian Oral Research·Rafaella Bastos LeiteCassiano Francisco Weege Nonaka
Jun 28, 2017·Journal of Lasers in Medical Sciences·Hoda RahimiHamideh Moravvej
Jun 11, 2019·Oxidative Medicine and Cellular Longevity·Dehai XianJianqiao Zhong
Jan 23, 2021·International Journal of Molecular Sciences·Jihyun LeeMiri Kim

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