PMID: 7526949Aug 1, 1994Paper

Angiogenesis: potential therapy for ischaemic disease

Current Opinion in Lipidology
J Symes, A D Sniderman

Abstract

The discovery of polypeptide mitogens capable of stimulating angiogenesis has inspired research addressing the potential of these agents in the treatment of ischaemic syndromes. Ischaemia or necrosis with associated inflammation has been found to increase the production of growth factors and receptor response. Administration of various exogenous angiogenic agents by several routes has resulted in enhanced growth of collateral vessels in animal models of myocardial, peripheral arterial, and cerebral insufficiency. Therapeutic angiogenesis may have an immense clinical potential.

Citations

Jan 1, 1995·Tissue Engineering·A D OuelletteA G Mikos
Jun 6, 2012·Comparative and Functional Genomics·R RakshambikaiN Srinivasan
Apr 1, 1997·Arteriosclerosis, Thrombosis, and Vascular Biology·M S Pepper

❮ Previous
Next ❯

Related Concepts

Related Feeds

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.