Angiographic adverse events during percutaneous coronary intervention fail to predict creatine kinase-MB elevation

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
James C BlankenshipElias A Iliadis

Abstract

We attempted to determine if aggressive detection of angiographic adverse events during coronary intervention could predict subsequent creatine kinase (CK)-MB elevations. During coronary intervention, both fluoroscopy and cine angiography were used to detect angiographic adverse events. At least one angiographic adverse event occurred in 133/251 (53%) of procedures. CK-MB elevation occurred in 24% of procedures. Slow flow during the procedure (P=0.002) and chest discomfort at the end of the procedure (P=0.007) were the strongest predictors of CK-MB elevation. Among procedures with no angiographic adverse events, CK-MB elevation occurred in 15/121 (12%), accounting for 25% of CK-MB elevations. We conclude that CK-MB elevation occurs after angiographically uncomplicated coronary interventions even when angiographic adverse events are aggressively detected. Routine monitoring of cardiac enzymes is necessary to detect all patients who will experience myocardial injury after coronary intervention.

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Citations

Nov 13, 2008·Scandinavian Cardiovascular Journal : SCJ·Zaid Al-DakhielHans Mickley
Nov 11, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Lloyd W Klein
Feb 14, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Rashed M AhmedTahir I Mohamed
Jul 31, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Issam D MoussaGregg W Stone
Sep 3, 2004·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Eric J Topol
Nov 2, 2014·Journal of the American Heart Association·Hanan IdrisJohn K French
Mar 1, 2005·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Lloyd W Klein
Apr 7, 2005·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mark A MatthewsIan C Gilchrist

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