Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT.

Biomedical Optics Express
Shaohua PiYali Jia

Abstract

Optical coherence tomography using visible-light sources can increase the axial resolution without the need for broader spectral bandwidth. Here, a high-resolution, fiber-based, visible-light optical coherence tomography system is built and used to image normal retina in rats and blood vessels in chicken embryo. In the rat retina, accurate segmentation of retinal layer boundaries and quantification of layer thicknesses are accomplished. Furthermore, three distinct capillary plexuses in the retina and the choriocapillaris are identified and the characteristic pattern of the nerve fiber layer thickness in rats is revealed. In the chicken embryo model, the microvascular network and a venous bifurcation are examined and the ability to identify and segment large vessel walls is demonstrated.

References

Nov 22, 1991·Science·D HuangC A Puliafito
Oct 1, 1981·The Journal of General Physiology·T F Sherman
Mar 1, 1995·Archives of Ophthalmology·M R HeeJ G Fujimoto
Aug 10, 2000·Neoplasia : an International Journal for Oncology Research·J G FujimotoM E Brezinski
Apr 3, 2001·Nature Medicine·W DrexlerJ G Fujimoto
Aug 15, 2002·Journal of Biomedical Optics·Maciej WojtkowskiAdolf F Fercher
Oct 28, 2003·Investigative Ophthalmology & Visual Science·Michel PaquesEric Vicaut
Jan 13, 2004·Journal of Biomedical Optics·Wolfgang Drexler
Sep 3, 2004·Vision Research·Rivka InzelbergAvinoam Ophir
Nov 24, 2006·Investigative Ophthalmology & Visual Science·Vivek J SrinivasanJames G Fujimoto
Nov 13, 2007·Journal of Biomedical Optics·Adam M ZyskStephen A Boppart
Jul 29, 2008·Investigative Ophthalmology & Visual Science·Vivek J SrinivasanJames G Fujimoto
Jan 12, 2010·Journal of Biomedical Optics·Yuuki Watanabe, Toshiki Itagaki
Aug 25, 2012·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Serkan KirbasMustafa Durmus
Nov 22, 2012·Investigative Ophthalmology & Visual Science·Diana C Lozano, Michael D Twa
Dec 18, 2012·Biomedical Optics Express·Yali JiaDavid Huang
May 15, 2013·Physics in Medicine and Biology·Steven L Jacques
Nov 2, 2014·Biomedical Optics Express·Ji YiHao F Zhang
Apr 22, 2015·Proceedings of the National Academy of Sciences of the United States of America·Yali JiaDavid Huang
Apr 25, 2015·Biomedical Optics Express·Shau Poh ChongVivek J Srinivasan
May 9, 2015·IEEE Transactions on Bio-medical Engineering·Siyu ChenHao F Zhang
Oct 3, 2015·Retina·Richard F SpaideNadia K Waheed
Mar 31, 2016·Developments in Ophthalmology·Philip J RosenfeldGiovanni Gregori
May 28, 2016·Biomedical Optics Express·Miao ZhangYali Jia
Jun 16, 2016·Journal of Biomedical Optics·Siyu ChenHao F Zhang
Jul 15, 2016·Investigative Ophthalmology & Visual Science·James Fujimoto, Eric Swanson
Jul 15, 2016·Investigative Ophthalmology & Visual Science·Simon S GaoDavid Huang
Jul 15, 2016·Investigative Ophthalmology & Visual Science·Ronil S ShahAmani A Fawzi
Aug 30, 2016·Biomedical Optics Express·Gangjun LiuDavid Huang

❮ Previous
Next ❯

Citations

Feb 1, 2019·Journal of Biomedical Optics·Shaohua PiYali Jia
May 14, 2020·Proceedings of the National Academy of Sciences of the United States of America·Shaohua PiYali Jia
Apr 21, 2018·Biomedical Optics Express·Shau Poh ChongVivek J Srinivasan
Jul 23, 2021·Progress in Retinal and Eye Research·Raphael LejoyeuxJay Chhablani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.