PMID: 2123904Dec 1, 1990Paper

Angiographic assessment of the infarct-related residual coronary stenosis after spontaneous or therapeutic thrombolysis

Journal of the American College of Cardiology
J Van LierdeF Van de Werf

Abstract

The severity of the infarct-related residual coronary stenosis after spontaneous or therapeutic thrombolysis was quantitatively assessed in 91 patients with an acute myocardial infarction who were allocated to treatment in the acute stage with either a thrombolytic agent (100 mg of recombinant tissue-type plasminogen activator given over 3 h, 49 patients) or a placebo (42 patients). Heparin and aspirin were given to both groups until angiography was performed. Digital subtracted images of the infarct-related coronary vessel were obtained 10 to 14 days after hospital admission and were subsequently analyzed with the use of a computer-assisted coronary stenosis measurement system. Neither treatment group differed significantly in age, gender or location of the culprit coronary lesion. Median values (90% range) in the thrombolysis and control groups were, respectively, 1.95 (0.9 to 5.3) mm versus 1.7 (0.9 to 3.4) mm for stenosis length; 1.4 (0.8 to 2.7) mm versus 1.4 (0.9 to 1.8) mm for minimal luminal diameter; 57% (36% to 75%) versus 58% (44% to 71%) for diameter obstruction; 82% (59% to 95%) versus 82% (68% to 92%) for geometric area obstruction; and 78% (58% to 91%) versus 79% (66% to 90%) for densitometric area obstruction. T...Continue Reading

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Citations

Jun 1, 1994·International Journal of Cardiac Imaging·C GrecoP L Prati
Dec 1, 1990·Journal of the American College of Cardiology·E Braunwald
Jul 1, 1993·Journal of the American College of Cardiology·N A PragerD R Abendschein
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Jun 10, 2009·International Heart Journal·Tetsuo SakaiYouichi Koboyashi
Apr 1, 1992·Cardiovascular Drugs and Therapy·M Verstraete
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Dec 12, 2012·Acute Cardiac Care·Liam M McCormickNick E J West
Oct 19, 2013·JACC. Cardiovascular Imaging·Giampaolo NiccoliRyan Berg
Dec 4, 1992·Annals of the New York Academy of Sciences·E Falk
Nov 30, 2018·European Heart Journal·Peter R Sinnaeve, Frans Van de Werf
Aug 7, 2019·Circulation. Cardiovascular Imaging·Alastair J MossPhilip D Adamson
Jan 27, 2019·Journal of the American College of Cardiology·Michelle C WilliamsEdward D Nicol

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