Angiographically undetected small hepatocellular carcinoma: clinicopathological characteristics, follow-up and treatment.

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
T SonodaK Sugimachi

Abstract

We studied 36 cases (38 nodules) of small hepatocellular carcinoma with special attention directed to detectability using angiography and histology. Among the 38 nodules, 31 nodules (81.6%) were evident. The remaining seven (18.4%) were not evident angiographically but were detected using ultrasonography and/or computed tomography, prior to angiography. An elevated level of serum alpha-fetoprotein also suggested a diagnosis of hepatocellular carcinoma. When comparisons were made between angiographically detected and undetected nodules, there was no statistically significant difference in parameters, including sex of the patient, tumor size, location of the tumor, positive rate for hepatitis B surface antigen, history of liver disease and values of alpha-fetoprotein. The small hepatocellular carcinomas not detected angiographically and evidenced only histologically had the following characteristics: (i) no fibrous capsule surrounding the nodules; (ii) well-differentiated tumors; (iii) replacing growth pattern of cancer cells, and (iv) remains of portal tracts within the tumor. The replacing growth pattern and the presence of portal tracts may correlate with the low detectability in angiography. When a definite diagnosis of angio...Continue Reading

References

Jul 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K Okuda
Jan 1, 1988·Digestive Diseases and Sciences·A MaringhiniL Pagliaro
Jan 1, 1985·Radiology·Y YumotoK Okuda
Sep 1, 1986·AJR. American Journal of Roentgenology·K TakayasuN Okazaki
Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K OkudaK Ohnishi

❮ Previous
Next ❯

Citations

Apr 22, 1997·International Journal of Cancer. Journal International Du Cancer·R NakashioG Kajiyama
Jul 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R YamaguchiM Kojiro
Apr 20, 2004·Journal of Hepatology·Takuji TorimuraMasamichi Kojiro
Feb 27, 2003·Journal of Gastroenterology and Hepatology·Maurizio PompiliGian Ludovico Rapaccini
Oct 31, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Gunjan GuhaLazar Mathew
Mar 1, 1993·Journal of Gastroenterology and Hepatology·T EzakiT Shirakusa
Nov 6, 2003·Journal of Clinical Pathology·K SugimachiM Tsuneyoshi
Sep 11, 2012·International Journal of Bioinformatics Research and Applications·Wilson Wen Bin GohMarek J Sergot
Mar 28, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Yoke Keong YongZuraini Ahmad
Mar 25, 2006·Fukushima Journal of Medical Science·Shuzo SatoYukio Sato
Jul 28, 2006·Cancer Treatment Reviews·Domenico RibattiFranco Dammacco
Feb 19, 2014·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Jun MutoYoshihiko Maehara
Jul 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·O NakashimaM Kojiro
Jun 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S SaitohH Kumada
Apr 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K TakenakaK Sugimachi
Jul 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K IkedaH Kumada
Jun 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K IkedaH Kumada
Dec 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K Taketa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.