Angiomyolipoma of the uterus associated with tuberous sclerosis: case report and review of the literature

Gynecologic Oncology
Aylin P CilMuzeyyen Gunes

Abstract

Angiomyolipoma (AML) is a rare benign tumor that occurs most commonly in the kidney. Only a few cases have been described in the uterus. We describe a 32-year-old woman with tuberous sclerosis who presented with irregular bleeding. Preoperatively, the lesions were confused with leiomyoma on ultrasound. At laparotomy, multiple circumscribed subserosal and intramural purplish lesions on the corpus uteri were noted leading to a diagnosis of uterine angiomyolipoma with the histological and immunohistochemical findings. In contrast to other reported uterine angiomyolipoma cases, HMB-45 melanoma-specific antibody immunoreactivity is demonstrated in the present case. The histopathologic diagnosis as well as immunohistochemical analysis is discussed here with a review of the literature.

References

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Citations

Mar 8, 2008·International Seminars in Surgical Oncology : ISSO·Oluwole Fadare
Sep 1, 2005·Cellular and Molecular Neurobiology·Jaroslaw Jozwiak, Sergiusz Jozwiak
Aug 10, 2006·Cellular and Molecular Neurobiology·Jaroslaw Jozwiak, Sergiusz Jozwiak
Jul 8, 2010·Journal of Clinical Ultrasound : JCU·Tracy GlassHeather J Holmes
Aug 30, 2018·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Susana Boronat, Ignasi Barber
Dec 3, 2009·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Xiaoduan ChenBingjian Lü
Feb 12, 2021·Archives of Gynecology and Obstetrics·Jiao WangDandan Wang
Jul 24, 2021·Indian Journal of Surgical Oncology·Neha Garg, Nadeem Tanveer

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