Angiomyolipoma of the uterus associated with tuberous sclerosis: case report and review of the literature

Gynecologic Oncology
Aylin P CilMuzeyyen Gunes


Angiomyolipoma (AML) is a rare benign tumor that occurs most commonly in the kidney. Only a few cases have been described in the uterus. We describe a 32-year-old woman with tuberous sclerosis who presented with irregular bleeding. Preoperatively, the lesions were confused with leiomyoma on ultrasound. At laparotomy, multiple circumscribed subserosal and intramural purplish lesions on the corpus uteri were noted leading to a diagnosis of uterine angiomyolipoma with the histological and immunohistochemical findings. In contrast to other reported uterine angiomyolipoma cases, HMB-45 melanoma-specific antibody immunoreactivity is demonstrated in the present case. The histopathologic diagnosis as well as immunohistochemical analysis is discussed here with a review of the literature.


Jan 1, 1989·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·W Sieiński
Apr 1, 1997·The Journal of Urology·M HanF F Marshall
Jun 15, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·F BonettiJ K Chan
Feb 15, 2002·Pathology International·H YaegashiH Sasano
May 1, 2002·Journal of Clinical Ultrasound : JCU·Heidi L BraunJohn W Seeds
Dec 7, 2002·Oncology Reports·J L SimmonsD M A Wallace

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