Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers after renal transplantation

Clinical Transplantation
C MorathM Zeier

Abstract

Renin-angiotensin system blockade retards the progression of diabetic and non-diabetic chronic kidney disease of the native kidneys. Though most patients suffer from a significant renal insufficiency (chronic kidney disease stage III) and a concomitant heart disease after renal transplantation, there is up to now no evidence supporting the use of inhibitors of the renin-angiotensin system in these patients. We wish to summarize the available evidence on the use of inhibitors of the renin-angiotensin system after renal transplantation. We specifically discuss potential beneficial as well as adverse effects of a renin-angiotensin system blockade. In addition, we review their influence on morphologic and biochemical markers as well as on renal function, graft and patient survival after renal transplantation.

Associated Clinical Trials

References

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Citations

Sep 8, 2012·Current Opinion in Hematology·William ArceseRaffaella Cerretti
Aug 24, 2012·Patient Related Outcome Measures·Artavazd TadevosyanVardan T Karamyan
Mar 12, 2013·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Antoine Barbari
Oct 13, 2016·Chest·Ayodeji AdegunsoyeRemzi Bag
Feb 26, 2019·Transplantation·Zahraa Mohammed-AliAna Konvalinka

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