Angiotensin-converting enzyme inhibitors prescription is associated with longer survival among patients hospitalized for congestive heart failure who have preserved systolic function: a long-term follow-up study

Journal of Cardiac Failure
Lilian Grigorian ShamagianJose Ramon Gonzalez-Juanatey

Abstract

The use of inhibitors of angiotensin-converting enzyme (ACE) is strongly indicated by a diagnosis of congestive heart failure (CHF) with deteriorated systolic function (SF), but their effects on patients with CHF but no systolic deterioration have not been clarified. We focused this study on the evaluation of the influence of ACE inhibitors on survival among CHF patients with preserved SF, but also determined the effect of these drugs on the prognosis of our patients with deteriorated SF. We studied 416 patients, aged 72.7 +/- 10.2 years, who between January 1, 1991, and December 31, 2001, were admitted to the cardiology service of a tertiary hospital for CHF and who fulfilled the requirements that left ventricular SF that had been evaluated echocardiographically during hospitalization was preserved and that data were available on medication at the time of their release from hospital. Two hundred four patients (49.0%) were men, 250 (60.8%) were hypertensive, and, in 171 (41.1%) cases, ischemic cardiopathy was the primary cause of the CHF. ACE inhibitors were prescribed to 210 patients (50.5%) on hospital release. Kaplan-Meier survival curve analysis showed that, among patients with preserved SF, a longer survival was associated...Continue Reading

References

Aug 10, 2000·European Journal of Heart Failure·J G ClelandJ Taylor

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Citations

Feb 5, 2008·Heart Failure Reviews·Yi-Da Tang, Stuart D Katz
Sep 4, 2008·Current Heart Failure Reports·Haroon A FarazJalal K Ghali
Aug 9, 2011·European Heart Journal·UNKNOWN Meta-analysis Global Group in Chronic Heart Failure (MAGGIC)
Jul 8, 2011·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Judy Ying ChenRichard S Chung
Mar 19, 2013·The American Journal of the Medical Sciences·Nadish GargMartin A Alpert
Sep 12, 2015·European Journal of Heart Failure·Joanne SimpsonUNKNOWN Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC)
Apr 7, 2009·Trends in Cardiovascular Medicine·Michael KindermannMichael Böhm
Aug 6, 2009·European Journal of Heart Failure·Jithendra B SomaratneGillian A Whalley
Mar 3, 2010·International Journal of Cardiology·Redi PeciniLars Køber
Mar 1, 2008·The American Journal of Cardiology·Christophe TribouilloyMichel Slama
Jul 19, 2014·Heart Failure Reviews·Chirag BavishiFranz H Messerli
Jan 5, 2011·Journal of Cardiovascular Pharmacology and Therapeutics·Christophe MeuneSimon Weber
Aug 8, 2018·European Heart Journal·Christopher J RushJohn J V McMurray

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