Angiotensin-converting enzyme-related cough among Chinese-Americans

The American Journal of Medicine
Daniel S TsengAshley O Coates

Abstract

Few studies have examined the relationship between ethnicity and tolerance of hypertension medications. We investigated the perception that Chinese-Americans may have a higher incidence of chronic cough from angiotensin-converting enzyme inhibitors. We searched electronic databases to identify patients who had received a new lisinopril prescription. This cohort was separated into 295 patients of Chinese descent and 4263 patients in the general population group with an instrument that used surnames to identify Chinese ethnicity. For those who discontinued lisinopril within 1 year, we reviewed medical records to determine reasons for discontinuation. We compared rates of discontinuation overall and due to cough by ethnic group (Chinese vs general population). The Chinese population was more likely to discontinue their medication (47%) than the general population (31%). When the cause for discontinuation was examined, cough was significantly higher among Chinese, with a relative risk of 2.53; 95% confidence interval (CI), 2.11-3.03. The risk for angioedema was <1%, and no difference in the risk of angioedema was found between the 2 groups. When controlled for age, sex, and smoking, the risk of cough among Chinese-Americans remaine...Continue Reading

References

Dec 1, 1989·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·E StrocchiE Ambrosioni
Jul 27, 1989·The New England Journal of Medicine
Sep 7, 1987·The Medical Journal of Australia·S Tugwell, G S Stokes
Dec 1, 1995·American Journal of Hypertension·D W Jones
Dec 7, 2002·Hypertension·Dongfeng GuUNKNOWN InterASIA Collaborative Group. The International Collaborative Study of Cardiovascular Disease in ASIA
Nov 12, 2003·The New England Journal of Medicine·Marc A PfefferUNKNOWN Valsartan in Acute Myocardial Infarction Trial Investigators
Nov 2, 2004·The New England Journal of Medicine·Anthony H BarnettUNKNOWN Diabetics Exposed to Telmisartan and Enalapril Study Group
Jan 18, 2005·The Journal of International Medical Research·S Evangelista, S Manzini
Apr 21, 2005·Drugs & Aging·Toshio Ogihara, Hiromi Rakugi
Mar 28, 2006·Medical Care·Hude QuanWilliam A Ghali
Aug 11, 2006·Health Services Research·Kevin Fiscella, Allen M Fremont
Apr 18, 2008·Current Atherosclerosis Reports·Deborah S MinorDaniel W Jones
Jan 23, 2016·Journal of the American Society of Hypertension : JASH·Isac C ThomasMatthew A Allison

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Citations

Sep 27, 2013·Aging Clinical and Experimental Research·Regina Helena Garcia MartinsAnete Branco
Sep 18, 2012·Current Medical Research and Opinion·Sverre E KjeldsenLisheng Liu
Feb 26, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Brittany StrakaNancy J Brown
Jul 21, 2011·Journal of the American Society of Hypertension : JASH·Mark J WrobelJoseph L Izzo
Jul 29, 2011·Journal of Zhejiang University. Science. B·Peter M Nilsson
Sep 19, 2018·Clinical Pharmacology and Therapeutics·Davor Vukadinović, Michael Böhm
Sep 12, 2012·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Andrew R L Medford
Jun 28, 2012·International Anesthesiology Clinics·Kyung W Park
Sep 8, 2010·Southern Medical Journal·James M Wooten
Oct 5, 2010·Southern Medical Journal·James M Wooten
Aug 14, 2021·Journal of the American College of Cardiology·Jonas GhouseMorten S Olesen

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