Animal- and human-based evidence for the protective effects of stem cell therapy against cardiovascular disorders

Journal of Cellular Physiology
Ali PooriaAlireza Gheini

Abstract

The increasing rate of mortality and morbidity because of cardiac diseases has called for efficient therapeutic needs. With the advancement in cell-based therapies, stem cells are abundantly studied in this area. Nearly, all sources of stem cells are experimented to treat cardiac injuries. Tissue engineering has also backed this technique by providing an advantageous platform to improve stem cell therapy. After in vitro studies, primary treatment-based research studies comprise small and large animal studies. Furthermore, these studies are implemented in human models in the form of clinical trials. Purpose of this review is to highlight the animal- and human-based studies, exploiting various stem cell sources, to treat cardiovascular disorders.

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Citations

Jul 10, 2020·Future Cardiology·Ali PooriaAlireza Gheini
Aug 18, 2021·The Clinical Respiratory Journal·Nina FarzanAlireza Zeraatchi
Oct 2, 2020·Cardiovascular & Hematological Disorders Drug Targets·Alireza GheiniAli Pooria
Dec 2, 2020·Cardiovascular & Hematological Disorders Drug Targets·Alireza NezamiSina Elahi
Dec 18, 2020·Cardiovascular & Hematological Disorders Drug Targets·Majid FirouziShiva Shafizadeh

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